中国是一个人口大国,随着老龄化问题的逐渐发展,繁衍生殖的矛盾愈发尖锐。近年来,女性生殖不良事件比率逐年上升,已经成为我们亟待解决的一大难题。输卵管是女性特有的生殖道结构之一,其微环境的差异或改变与发生生殖不良事件具有一定...中国是一个人口大国,随着老龄化问题的逐渐发展,繁衍生殖的矛盾愈发尖锐。近年来,女性生殖不良事件比率逐年上升,已经成为我们亟待解决的一大难题。输卵管是女性特有的生殖道结构之一,其微环境的差异或改变与发生生殖不良事件具有一定的相关性,本文将从细胞、液体环境等方面对输卵管微环境与女性生殖不良事件进行综述,以期为相关研究和临床实践提供参考。China is a populous country, and with the gradual development of the ageing problem, the contradiction of reproduction and reproduction has become more and more acute. In recent years, the rate of female reproductive adverse events has been increasing year by year and has become a major problem that we need to solve. The fallopian tube is one of the unique female reproductive tract structures, and differences or changes in its microenvironment have a certain correlation with the occurrence of reproductive adverse events. In this paper, we will review the microenvironment of the fallopian tube and female reproductive adverse events in terms of the cellular and fluid environments, with a view to providing references to related research and clinical practice.展开更多
目的:系统评价2012年至今中国成年女性(≥18岁)宫颈癌患病率。方法:计算机检索PubMed、Embase、The Cochrane Library、Web of Science、中国知网(CNKI)、万方、维普及中国生物医学文献数据库(CBM),收集关于中国成年女性宫颈癌患病率的...目的:系统评价2012年至今中国成年女性(≥18岁)宫颈癌患病率。方法:计算机检索PubMed、Embase、The Cochrane Library、Web of Science、中国知网(CNKI)、万方、维普及中国生物医学文献数据库(CBM),收集关于中国成年女性宫颈癌患病率的横断面研究,检索时限为2012年1月至2022年6月。由2名研究员独立筛选文献,提取资料,进行偏倚风险评价,采用Stata 17.0软件对纳入的研究进行Meta分析。结果:共纳入104个横断面研究,包括3305476例研究对象,1426例中国成年女性宫颈癌患者。Meta分析结果显示,近10年中国成年女性宫颈癌患病率为0.08%[95%CI(0.08%,0.09%)]。亚组分析结果:以经济带分组,东部经济带女性宫颈癌患病率为0.07%[95%CI(0.07%,0.08%)],中部经济带为0.08%[95%CI(0.07%,0.10%)],西部经济带为0.10%[95%CI(0.09%,0.11%)]。以居住地分组,城市女性宫颈癌患病率为0.08%[95%CI(0.08%,0.09%)],农村女性为0.08%[95%CI(0.07%,0.09%)]。以调查年份分组,2012~2016年度女性宫颈癌患病率为0.08%[95%CI(0.07%,0.08%)],2017~2022年度为0.10%[95%CI(0.09%,0.11%)]。结论:近10年我国成年女性(≥18岁)宫颈癌患病率呈上升趋势,我国宫颈癌患病率与经济发展呈负相关。展开更多
文摘中国是一个人口大国,随着老龄化问题的逐渐发展,繁衍生殖的矛盾愈发尖锐。近年来,女性生殖不良事件比率逐年上升,已经成为我们亟待解决的一大难题。输卵管是女性特有的生殖道结构之一,其微环境的差异或改变与发生生殖不良事件具有一定的相关性,本文将从细胞、液体环境等方面对输卵管微环境与女性生殖不良事件进行综述,以期为相关研究和临床实践提供参考。China is a populous country, and with the gradual development of the ageing problem, the contradiction of reproduction and reproduction has become more and more acute. In recent years, the rate of female reproductive adverse events has been increasing year by year and has become a major problem that we need to solve. The fallopian tube is one of the unique female reproductive tract structures, and differences or changes in its microenvironment have a certain correlation with the occurrence of reproductive adverse events. In this paper, we will review the microenvironment of the fallopian tube and female reproductive adverse events in terms of the cellular and fluid environments, with a view to providing references to related research and clinical practice.
