Cardiolipin （CL）, a lipid specific to mitochondrial inner membrane, presents in this membrane in the range of 20—25% of its total lipids. CL is a lipid with negative charges, rich in unsaturated fatty acyl chains, ...Cardiolipin （CL）, a lipid specific to mitochondrial inner membrane, presents in this membrane in the range of 20—25% of its total lipids. CL is a lipid with negative charges, rich in unsaturated fatty acyl chains, and can undergo non-bilayer phase transition, such as hexagonal (H<sub>11</sub>) phase under certain conditions. It has been reported that the activity for respiratory chain components, cytochrome c oxidase for example, and展开更多
Cardiolipin (CL) with two negative charges and four unsaturated fatty acyl chains is a phosphalipid specific to mitochondrial inner membrane. With the static interaction cytochrome c can be bound to CL. Because of the...Cardiolipin (CL) with two negative charges and four unsaturated fatty acyl chains is a phosphalipid specific to mitochondrial inner membrane. With the static interaction cytochrome c can be bound to CL. Because of the activity of cytochrome c oxidase, CL is required to be tightly bound to this enzyme. However, the effect of CL on the展开更多
基金Project supported by the National Natural Science Foundation of China.
文摘Cardiolipin （CL）, a lipid specific to mitochondrial inner membrane, presents in this membrane in the range of 20—25% of its total lipids. CL is a lipid with negative charges, rich in unsaturated fatty acyl chains, and can undergo non-bilayer phase transition, such as hexagonal (H<sub>11</sub>) phase under certain conditions. It has been reported that the activity for respiratory chain components, cytochrome c oxidase for example, and
基金Project supported by the National Natural Science Foundation of China
文摘Cardiolipin (CL) with two negative charges and four unsaturated fatty acyl chains is a phosphalipid specific to mitochondrial inner membrane. With the static interaction cytochrome c can be bound to CL. Because of the activity of cytochrome c oxidase, CL is required to be tightly bound to this enzyme. However, the effect of CL on the
