商业Pt/C是最常用的析氢催化剂,但其成本高昂,储量有限,因此降低Pt负载量以降低成本是实现长久发展的关键。在Pt中引入其它金属组分对催化剂进行表面修饰等是当下对Pt基纳米催化剂表面改性的研究热点。本论文以酸处理的科琴黑为载体,氯...商业Pt/C是最常用的析氢催化剂,但其成本高昂,储量有限,因此降低Pt负载量以降低成本是实现长久发展的关键。在Pt中引入其它金属组分对催化剂进行表面修饰等是当下对Pt基纳米催化剂表面改性的研究热点。本论文以酸处理的科琴黑为载体,氯亚铂酸钾和硝酸镍为主要金属催化剂前驱体,通过超声辅助还原法将金属离子Pt2+和Ni2+还原为PtNi合金,并以纳米团簇的形式沉积于载体上,成功制备出高效、稳定的酸处理PtNi纳米团簇催化剂(PtNiNC-acid)。研究发现,当电流密度为50 mA cm−2时,PtNiNC-acid的过电位为33 mV;PtNiNC-acid在10 mA cm−2和100 mA cm−2的电流密度下,分别具有55 h和45 h的优良稳定性,这证明了PtNiNC-acid在碱性溶液中具有较高的HER活性和稳定性。Commercial Pt/C is the most commonly used hydrogen evolution catalyst, but its cost is high and its reserves are limited, so reducing Pt load to reduce costs is the key to achieve long-term development. The introduction of other metal components in Pt to modify the surface of the catalyst is the current research focus on the surface modification of Pt based nano-catalyst. In this paper, acid treated Keqin black as the carrier, potassium chlorophosphite and nickel nitrate as the main metal catalyst precursor, the metal ions Pt2+ and Ni2+ were reduced to PtNi alloy by ultrasonic assisted reduction method, and deposited on the carrier in the form of nano-clusters. An efficient and stable acid-treated PtNi nanocluster catalyst (PtNiNC-acid) was successfully prepared. It was found that the overpotential of PtNiNC-acid was 33 mV when the current density was 50 mA cm−2. The excellent stability of PtNiNC-acid at the current densities of 10 mA cm−2 and 100 mA cm−2 for 55 h and 45 h, respectively, proves that PtNiNC-acid has high HER activity and stability in alkaline solutions.展开更多
背景与目的:胎盘部位滋养细胞肿瘤(placental site trophoblastic tumor,PSTT)是罕见的妇科恶性肿瘤,由于PSTT在子宫内独特的浸润方式和对化疗不敏感特性,全子宫切除是首选的手术方式。本研究旨在探讨Ⅰ期PSTT患者保守手术治疗的可行性...背景与目的:胎盘部位滋养细胞肿瘤(placental site trophoblastic tumor,PSTT)是罕见的妇科恶性肿瘤,由于PSTT在子宫内独特的浸润方式和对化疗不敏感特性,全子宫切除是首选的手术方式。本研究旨在探讨Ⅰ期PSTT患者保守手术治疗的可行性和安全性。方法:纳入2015年1月-2021年12月复旦大学附属妇产科医院收治的Ⅰ期PSTT病例,同时分别以“placental site trophoblastic tumor”和“case”、“胎盘部位滋养细胞肿瘤”和“例”为关键词在PubMed和中国知网(CNKI)中检索1990年1月-2021年12月发表的接受保守手术治疗的Ⅰ期PSTT个案报道和系统病例报告,收集患者的临床病理学资料,并进行回顾性分析。结果:共纳入复旦大学附属妇产科医院收治的符合标准的病例10例,中位年龄为27岁,最常见的症状为不规则阴道出血(70.0%),中位诊断距离前次妊娠时间间隔(interval since antecedent pregnancy,ISAP)为14.5个月,中位β-绒毛膜促性腺激素(β-human chorionic gonadotrophin,β-hCG)水平为124.51 mU/mL,病灶直径为0.8~8.0 cm。复旦大学附属妇产科医院收治的10例患者经初始治疗后均获得完全缓解,平均随访时间为48.1个月,均未复发。3例患者治疗后自然受孕,其中2例足月妊娠分娩,1例因计划外妊娠行人工流产。文献复习PSTT病例显示出类似的临床病理学分布特征和疾病转归。结论:保守手术可以作为部分Ⅰ期PSTT患者的一种替代治疗方法,但需更多研究提供证据。展开更多
文摘商业Pt/C是最常用的析氢催化剂,但其成本高昂,储量有限,因此降低Pt负载量以降低成本是实现长久发展的关键。在Pt中引入其它金属组分对催化剂进行表面修饰等是当下对Pt基纳米催化剂表面改性的研究热点。本论文以酸处理的科琴黑为载体,氯亚铂酸钾和硝酸镍为主要金属催化剂前驱体,通过超声辅助还原法将金属离子Pt2+和Ni2+还原为PtNi合金,并以纳米团簇的形式沉积于载体上,成功制备出高效、稳定的酸处理PtNi纳米团簇催化剂(PtNiNC-acid)。研究发现,当电流密度为50 mA cm−2时,PtNiNC-acid的过电位为33 mV;PtNiNC-acid在10 mA cm−2和100 mA cm−2的电流密度下,分别具有55 h和45 h的优良稳定性,这证明了PtNiNC-acid在碱性溶液中具有较高的HER活性和稳定性。Commercial Pt/C is the most commonly used hydrogen evolution catalyst, but its cost is high and its reserves are limited, so reducing Pt load to reduce costs is the key to achieve long-term development. The introduction of other metal components in Pt to modify the surface of the catalyst is the current research focus on the surface modification of Pt based nano-catalyst. In this paper, acid treated Keqin black as the carrier, potassium chlorophosphite and nickel nitrate as the main metal catalyst precursor, the metal ions Pt2+ and Ni2+ were reduced to PtNi alloy by ultrasonic assisted reduction method, and deposited on the carrier in the form of nano-clusters. An efficient and stable acid-treated PtNi nanocluster catalyst (PtNiNC-acid) was successfully prepared. It was found that the overpotential of PtNiNC-acid was 33 mV when the current density was 50 mA cm−2. The excellent stability of PtNiNC-acid at the current densities of 10 mA cm−2 and 100 mA cm−2 for 55 h and 45 h, respectively, proves that PtNiNC-acid has high HER activity and stability in alkaline solutions.
文摘背景与目的:胎盘部位滋养细胞肿瘤(placental site trophoblastic tumor,PSTT)是罕见的妇科恶性肿瘤,由于PSTT在子宫内独特的浸润方式和对化疗不敏感特性,全子宫切除是首选的手术方式。本研究旨在探讨Ⅰ期PSTT患者保守手术治疗的可行性和安全性。方法:纳入2015年1月-2021年12月复旦大学附属妇产科医院收治的Ⅰ期PSTT病例,同时分别以“placental site trophoblastic tumor”和“case”、“胎盘部位滋养细胞肿瘤”和“例”为关键词在PubMed和中国知网(CNKI)中检索1990年1月-2021年12月发表的接受保守手术治疗的Ⅰ期PSTT个案报道和系统病例报告,收集患者的临床病理学资料,并进行回顾性分析。结果:共纳入复旦大学附属妇产科医院收治的符合标准的病例10例,中位年龄为27岁,最常见的症状为不规则阴道出血(70.0%),中位诊断距离前次妊娠时间间隔(interval since antecedent pregnancy,ISAP)为14.5个月,中位β-绒毛膜促性腺激素(β-human chorionic gonadotrophin,β-hCG)水平为124.51 mU/mL,病灶直径为0.8~8.0 cm。复旦大学附属妇产科医院收治的10例患者经初始治疗后均获得完全缓解,平均随访时间为48.1个月,均未复发。3例患者治疗后自然受孕,其中2例足月妊娠分娩,1例因计划外妊娠行人工流产。文献复习PSTT病例显示出类似的临床病理学分布特征和疾病转归。结论:保守手术可以作为部分Ⅰ期PSTT患者的一种替代治疗方法,但需更多研究提供证据。
