血瘀证是冠心病发病的主要因素之一,肠道菌群可以影响冠心病血瘀证的发生与发展。“心与小肠相表里”是《黄帝内经》对二者关系的总结概括,小肠代谢失常,导致津液输布障碍,成痰成瘀,痹阻心脉可以导致胸痹的发生。活血化瘀药物的应用对...血瘀证是冠心病发病的主要因素之一,肠道菌群可以影响冠心病血瘀证的发生与发展。“心与小肠相表里”是《黄帝内经》对二者关系的总结概括,小肠代谢失常,导致津液输布障碍,成痰成瘀,痹阻心脉可以导致胸痹的发生。活血化瘀药物的应用对其有显著疗效,防止冠心病血瘀证的进一步发展,也使小肠的生理功能恢复正常。该文旨在从“心与小肠相表里”视角探讨心脏、小肠和冠心病血瘀证的相关性,为防治冠心病血瘀证提供理论基础和新的思路方法。Blood stasis is one of the main factors in the development of coronary heart disease, and intestinal flora can affect the occurrence and development of blood stasis in coronary heart disease. “The heart and the small intestine are mutually exclusive” is the “Huangdi Neijing” on the relationship between the two summarized, the small intestine metabolic disorders, resulting in fluid distribution obstacles, into phlegm into blood stasis, paralysis of the cardiac veins can lead to the occurrence of thoracic paralysis. The application of drugs to activate blood circulation and eliminate blood stasis can have significant therapeutic effects, preventing the further development of blood stasis in coronary heart disease and restoring the physiological function of the small intestine to normal. The aim of this article is to discuss the correlation between heart, small intestine and coronary blood stasis from the perspective of “heart and small intestine are mutually exclusive”, so as to provide theoretical basis and new ideas and methods for the prevention and treatment of coronary blood stasis.展开更多
肠道菌群及其代谢产物与心血管的联系逐渐被证明,肠道菌群及其代谢产物可以影响RAAS系统,继而对机体的血压水平进行调节。且中医学理论中指出人的五脏六腑时刻处于动态平衡。藏象理论中提出心不仅与肾水火相济,亦与小肠互为表里。当心...肠道菌群及其代谢产物与心血管的联系逐渐被证明,肠道菌群及其代谢产物可以影响RAAS系统,继而对机体的血压水平进行调节。且中医学理论中指出人的五脏六腑时刻处于动态平衡。藏象理论中提出心不仅与肾水火相济,亦与小肠互为表里。当心的脏腑功能失调,肾与小肠的脏腑功能紊乱,继而促进病理产物的产生,致使脉道不利,导致高血压病的发生与发展,反之亦然。本文章论述了肠–心–肾轴的相关中医理论依据与肠道菌群及其代谢产物对血压的调节作用,以期为高血压病的预防以及治疗提供新思路。The link between intestinal flora and its metabolites and cardiovascular disease has been gradually proved, and intestinal flora and its metabolites can affect the RAAS system, which then regulates the blood pressure level of the body. And the theory of Chinese medicine points out that the five viscera and six bowels of a person are always in dynamic balance. Tibetan theory suggests that the heart not only with the kidneys, water and fire, but also with the small intestine for each other. When the heart’s visceral dysfunction, kidney and small intestine visceral dysfunction, and then promote the production of pathological products, resulting in the pulse channel is unfavorable, leading to the occurrence and development of hypertension, and vice versa. The present article discusses the theoretical basis of the intestinal-cardiac-kidney axis in Chinese medicine and the role of intestinal flora and its metabolites in the regulation of blood pressure, with a view to providing new ideas for the prevention and treatment of hypertension.展开更多
文摘血瘀证是冠心病发病的主要因素之一,肠道菌群可以影响冠心病血瘀证的发生与发展。“心与小肠相表里”是《黄帝内经》对二者关系的总结概括,小肠代谢失常,导致津液输布障碍,成痰成瘀,痹阻心脉可以导致胸痹的发生。活血化瘀药物的应用对其有显著疗效,防止冠心病血瘀证的进一步发展,也使小肠的生理功能恢复正常。该文旨在从“心与小肠相表里”视角探讨心脏、小肠和冠心病血瘀证的相关性,为防治冠心病血瘀证提供理论基础和新的思路方法。Blood stasis is one of the main factors in the development of coronary heart disease, and intestinal flora can affect the occurrence and development of blood stasis in coronary heart disease. “The heart and the small intestine are mutually exclusive” is the “Huangdi Neijing” on the relationship between the two summarized, the small intestine metabolic disorders, resulting in fluid distribution obstacles, into phlegm into blood stasis, paralysis of the cardiac veins can lead to the occurrence of thoracic paralysis. The application of drugs to activate blood circulation and eliminate blood stasis can have significant therapeutic effects, preventing the further development of blood stasis in coronary heart disease and restoring the physiological function of the small intestine to normal. The aim of this article is to discuss the correlation between heart, small intestine and coronary blood stasis from the perspective of “heart and small intestine are mutually exclusive”, so as to provide theoretical basis and new ideas and methods for the prevention and treatment of coronary blood stasis.
文摘肠道菌群及其代谢产物与心血管的联系逐渐被证明,肠道菌群及其代谢产物可以影响RAAS系统,继而对机体的血压水平进行调节。且中医学理论中指出人的五脏六腑时刻处于动态平衡。藏象理论中提出心不仅与肾水火相济,亦与小肠互为表里。当心的脏腑功能失调,肾与小肠的脏腑功能紊乱,继而促进病理产物的产生,致使脉道不利,导致高血压病的发生与发展,反之亦然。本文章论述了肠–心–肾轴的相关中医理论依据与肠道菌群及其代谢产物对血压的调节作用,以期为高血压病的预防以及治疗提供新思路。The link between intestinal flora and its metabolites and cardiovascular disease has been gradually proved, and intestinal flora and its metabolites can affect the RAAS system, which then regulates the blood pressure level of the body. And the theory of Chinese medicine points out that the five viscera and six bowels of a person are always in dynamic balance. Tibetan theory suggests that the heart not only with the kidneys, water and fire, but also with the small intestine for each other. When the heart’s visceral dysfunction, kidney and small intestine visceral dysfunction, and then promote the production of pathological products, resulting in the pulse channel is unfavorable, leading to the occurrence and development of hypertension, and vice versa. The present article discusses the theoretical basis of the intestinal-cardiac-kidney axis in Chinese medicine and the role of intestinal flora and its metabolites in the regulation of blood pressure, with a view to providing new ideas for the prevention and treatment of hypertension.