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海藻功能性食品对小鼠高脂血症预防作用的研究 被引量:3
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作者 罗宁泰 张泽良 +8 位作者 邓芳 王婷 刘子菁 陶委琦 陈韵竹 陈昱妙 孙诗怡 廖心童 黄建军 《畜牧与饲料科学》 2017年第3期42-45,共4页
[目的]探究以海带、大蒜、姜等为原料的海藻功能性食品的降血脂作用。[方法]将60只昆明种小鼠分为正常对照组、高脂模型对照组、血脂康阳性对照组、海藻功能性食品低剂量组、海藻功能性食品高剂量组。其中,正常对照组每天每只喂食普通饲... [目的]探究以海带、大蒜、姜等为原料的海藻功能性食品的降血脂作用。[方法]将60只昆明种小鼠分为正常对照组、高脂模型对照组、血脂康阳性对照组、海藻功能性食品低剂量组、海藻功能性食品高剂量组。其中,正常对照组每天每只喂食普通饲料8 g,其余4组喂食等量的高脂饲料。采用高脂饲料诱导小鼠建立高脂血症模型的同时,在血脂康阳性对照组、海藻功能性食品低剂量组、海藻功能性食品高剂量组小鼠的日粮中分别添加血脂康164 mg/(kg·BW·d)和海藻功能性食品307、614 mg/(kg·BW·d)进行预防性给药,28 d后,检测小鼠血清中总胆固醇(total cholesterol,TC)、甘油三酯(triglycerides,TG)和高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)含量,并计算动脉粥样硬化指数(atherosclerosis index,AI)、肝指数、脾指数。[结果]与高脂模型对照组相比,海藻功能性食品高剂量组小鼠TC、TG、AI分别下降了18.33%、22.16%、40.7%,HDL-C升高了34.9%,肝指数、脾指数分别下降了12.5%、13.3%。[结论]海藻功能性食品可显著抑制高脂饲料小鼠血浆TC、TG、AI的升高与HDL-C降低,可预防试验小鼠高脂血症与动脉粥样硬化的形成,其作用呈现出一定的量效关系。 展开更多
关键词 海藻 功能性食品 降血脂 动脉粥样硬化
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国家集采常态化制度逐渐成熟明朗 被引量:15
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作者 郝梦娇 王贺 +1 位作者 罗宁泰 江滨 《中国卫生》 2020年第6期78-81,共4页
经过第一批国家组织药品集中带量采购的试点和扩围工作,国家集采常态化制度逐渐成熟明朗。有关部门在总结了前期工作的经验和问题后,进一步完善了第二批集采政策及规则。深入分析优化后的第二批集采规则要点,对于更好地预测后续常态化... 经过第一批国家组织药品集中带量采购的试点和扩围工作,国家集采常态化制度逐渐成熟明朗。有关部门在总结了前期工作的经验和问题后,进一步完善了第二批集采政策及规则。深入分析优化后的第二批集采规则要点,对于更好地预测后续常态化的集采模式具有重要的现实意义。 展开更多
关键词 扩围 经验和问题 常态化 集采 带量采购 前期工作 分析优化 明朗
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The effects of the National Drug Pooled Procurement(NDPP)pilot program in China 被引量:8
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作者 Ningtai Luo Jianying Yue +1 位作者 Ruojing Zhou Bin Jiang 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2022年第3期212-217,共6页
In 2018,the Chinese government identified four municipalities and seven sub-provincial cities for the implementation of the National Drug Pooled Procurement(NDPP)pilot program(the“4+7”policy).In the present study,we... In 2018,the Chinese government identified four municipalities and seven sub-provincial cities for the implementation of the National Drug Pooled Procurement(NDPP)pilot program(the“4+7”policy).In the present study,we analyzed the effects of the“4+7”policy with data of 25 pilot drugs from the National Healthcare Security Administration(NHSA)from the aspects of drug price,volume,and expenditure.After the implementation of the policy,the average price of total and winning drugs was decreased by 54.47%and 73.82%,respectively,while the DDDc of non-winning drugs was decreased by only 1.54%,and the DDDc of uncertificated generic drugs was increased 83.18%.The DDDs indicating the volume of total and winning drugs was increased by 21.18%and 353.98%,respectively,and the DDDs of non-winning drugs was decreased by 61.35%.The costs of total and non-winning drugs were decreased by 44.83%and 61.94%,respectively,and the cost of winning drugs was increased by 18.87%.The“4+7”policy reduced the price and cost of pilot drugs and improved the affordability and accessibility of drugs.However,there were also problems with unexpected excessive price increases of uncertificated generic drugs and relatively high prices of non-winning products.Therefore,we highly suggested promoting the normalization and institutionalization of pooled drug procurement,enhancing the administrative capacity of local procurement platforms,and strengthening monitoring the price of non-winning,especially for the uncertificated generic drugs. 展开更多
关键词 National Drug Pooled Procurement(NDPP)pilot program The“4+7”policy Pooled procurement Volume-based procurement Implementation effects
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“四批五轮”后的药品集采续约方案 被引量:3
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作者 孙冬悦 罗宁泰 江滨 《中国卫生》 2021年第3期34-35,共2页
药品集中带量采购已经开展“4+7”试点、试点扩围等四批五轮,标期设定为1年~3年。采购标期结束后,如何开展规范化的续约。
关键词 扩围 规范化 药品 五轮 采购 试点
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Analysis of reimbursement policy for outpatient chronic diseases in basic medical insurance for urban residents in China provincial capitals 被引量:1
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作者 Ningtai Luo Yajuan Xiong +2 位作者 Li Liu Bin Jiang Jianying Yue 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2021年第10期845-850,共6页
Reimbursement policy for outpatient chronic diseases is an important part of the basic medical insurance scheme in China. The reimbursement policy for outpatient chronic diseases in basic medical insurance for urban r... Reimbursement policy for outpatient chronic diseases is an important part of the basic medical insurance scheme in China. The reimbursement policy for outpatient chronic diseases in basic medical insurance for urban residents of provincial capitals in China were analyzed from the perspectives of disease types, benefits package, qualification and health service access. Proposals to improve policy design, establish standardized disease inclusion criteria and set reasonable benefits package, strengthen management and complete supporting policy, strengthen policy coordination were put forward according the existing problems such as fragmented policy, great difference in disease types and benefit package, supervision difficulty, incomplete policy framework and lack of policy coordination. 展开更多
关键词 Outpatient chronic diseases Basic medical insurance Reimbursement policy
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第二批国家集采企业报价模式
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作者 郝梦娇 王贺 +1 位作者 罗宁泰 江滨 《中国卫生》 2020年第6期89-90,共2页
第二批国家集采竞价规则根据全国药品集中采购文件(GYYD2019-2),本轮集采为每个品种规格设定最高限价,有效报价不应高于最高限价,并满足以下三个条件之一:(1)熔断价规则:企业报价超过最低报价1.8倍者直接被淘汰出局。
关键词 最高限价 药品集中采购 品种规格 最低报价 企业报价 报价模式 集采
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Research on the sharing mechanism of drug price information in China-from the perspective of intergovernmental information sharing
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作者 Shuai Wang Ting Yin +2 位作者 Ningtai Luo Xiaoping Liu Bin Jiang 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2018年第8期582-587,共6页
Establishment of sharing mechanism for drug price information to guarantee the construction of a unified cross-departmental price information platform is a new national policy after Chinese government abandoned drug p... Establishment of sharing mechanism for drug price information to guarantee the construction of a unified cross-departmental price information platform is a new national policy after Chinese government abandoned drug price control. Based on the theory of intergovernmental information sharing, this study aimed to investigate the drug price information sharing mechanism in China through literature research and stakeholder interviews, which included institution guarantee mechanism, department coordination mechanism and technical support mechanism. 展开更多
关键词 Drug price Information sharing mechanism Cross-departmental price information platform Intergovernmental information sharing
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