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A MICROCALORIMETRIC STUDY ON THE EFFECT OF INHIBITORS ON ENZYME——DETERMINATION OF INHIBITION CONSTANT K_i 被引量:1
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作者 胡粹青 刘云娜 +1 位作者 王苏民 林治焕 《Chinese Science Bulletin》 SCIE EI CAS 1984年第5期610-615,共6页
In energy eonservatisn, release and transduction of ATPase are of vital importance. A microcalorimetric method was used to study the inhibitory effect of halogen compounds, e.g. ICH2COONa, BrCH2COONa, ICH2CONH2, on th... In energy eonservatisn, release and transduction of ATPase are of vital importance. A microcalorimetric method was used to study the inhibitory effect of halogen compounds, e.g. ICH2COONa, BrCH2COONa, ICH2CONH2, on the activity of Mg2+ dependent soluble ATPase (F1) from pig heart mitochondria. It was found that the degree 展开更多
关键词 MITOCHONDRIA ATPASE VITAL TRANSDUCTION inhib REVERSIBLE MALEATE amplifier 川乌 deter
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THE INTERACTION OF ANISODAMINE WITH PHOSPHOLIPID MEMBRANES
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作者 王苏民 黄芬 +3 位作者 傅亚珍 章正廉 董仁杰 胡粹青 《Chinese Science Bulletin》 SCIE EI CAS 1984年第4期529-532,共4页
Biomembrane, according to our present view, consists of a lipid bilayer matrix with which membrane-bound proteins are associated. There is a widening belief that membrane is the preliminary site of action of drugs on ... Biomembrane, according to our present view, consists of a lipid bilayer matrix with which membrane-bound proteins are associated. There is a widening belief that membrane is the preliminary site of action of drugs on cells. The drug-membrane interaction are generally considered as hydrogen bond, electrostatic and hydrophobic forces in nature and, in turn, resulting in an alteration of the physico-chemical behavior and physiological function of the membrane. 展开更多
关键词 preliminary PHYSIOLOGICAL BELIEF ALTERATION HYDROPHOBIC Chengdu eliminate neutral LIPID electrostatic
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THE EFFECT OF HYOSCYAMINE DRUGS ON THE FLUIDITY OF PHOSPHOLIPID MODEL MEMBRANES BY A DIFFERENTIAL SCANNING CALORIMETRIC METHOD
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作者 王苏民 黄芬 +3 位作者 付亚珍 章正廉 董仁杰 胡粹青 《Chinese Science Bulletin》 SCIE EI CAS 1983年第5期693-696,共4页
Hyoscyamus niger L., medicinal herbs recorded in the famous ancient Chinese medical book Compendium of Materia Medica, are widely dispersed all over China. Anisodamine and anisodine are newly isolated from these medic... Hyoscyamus niger L., medicinal herbs recorded in the famous ancient Chinese medical book Compendium of Materia Medica, are widely dispersed all over China. Anisodamine and anisodine are newly isolated from these medicinal herbs and synthesized first by Chinese scientists. Drugs also belonging to this group are scopolamine 展开更多
关键词 dispersed NIGER HEPES medicinal ancient desired FLUIDITY indium heating MOLAR
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