A phytochemical investigation on the aerial parts of Waltheria indica Linn.led to the isolation of 16 compounds,including five terpenoids(1–5),four coumarins(6–9),six flavonoids(10–15),and one phenylpropanoid glyco...A phytochemical investigation on the aerial parts of Waltheria indica Linn.led to the isolation of 16 compounds,including five terpenoids(1–5),four coumarins(6–9),six flavonoids(10–15),and one phenylpropanoid glycoside(16).The structures of these compounds were identified by spectroscopic data analysis and comparison with those reported in the literatures.Except for 12 and 15,all the compounds were isolated from W.indica for the first time.Moreover,coumarins were firstly reported to be obtained from this herb.The NO production inhibitory activities of all the isolated compounds in LPS-induced BV-2 cells were also presented.展开更多
基金National Natural Science Foundation of China(Grant No.81473106 and 81773864)The Drug Innovation Major Project of China(Grant No.2018ZX09711001-008-003)
文摘A phytochemical investigation on the aerial parts of Waltheria indica Linn.led to the isolation of 16 compounds,including five terpenoids(1–5),four coumarins(6–9),six flavonoids(10–15),and one phenylpropanoid glycoside(16).The structures of these compounds were identified by spectroscopic data analysis and comparison with those reported in the literatures.Except for 12 and 15,all the compounds were isolated from W.indica for the first time.Moreover,coumarins were firstly reported to be obtained from this herb.The NO production inhibitory activities of all the isolated compounds in LPS-induced BV-2 cells were also presented.
