For electronic microscopic observation, we found SSV-transformed NIH 3T3 cells were different from non-transformed cells. In SSV-transformed NIH 3T3 cells nuclei cytoplasma ratio was increased and in cytoplasma the ri...For electronic microscopic observation, we found SSV-transformed NIH 3T3 cells were different from non-transformed cells. In SSV-transformed NIH 3T3 cells nuclei cytoplasma ratio was increased and in cytoplasma the ribosomes (polyribosomes were attached to the swollen rough endoplasmic reticulum. It was likely that ribosomes were lined together functionally and structionally to produce specific protein (PDGF-like protein).展开更多
A well-known Chinese traditional drug, decoction of wick of sun-flower stem, has been used to treat cancer and certain other diseases.1,2 Animal experiments in mice showed that transplantation of Sarcoma 180 (S180) an...A well-known Chinese traditional drug, decoction of wick of sun-flower stem, has been used to treat cancer and certain other diseases.1,2 Animal experiments in mice showed that transplantation of Sarcoma 180 (S180) and of Uterus cervical cancer 14 (U14) were signlflcanly inhibited by this decoction. The Inhibition rates of tumor weight were 33 -81 % and in about 6 - 20% of treated mice, complete tumor regression has been demonstrated. So tar no acute toxic side-effect was noted. This is in contrast to most of the antitumor chemltherapeutic drugs known to produce different degrees of toxlcity or induce Immunosuppression as a side effect. For this reason, we have undertaken the present study.展开更多
本文研究了1986—1989年间BALB/C小鼠发生的两次散发流行和一次有BALB/C及NIH鼠群暴发流行的EDIM(Epizootic diarrhea of infant mice)。经过电镜、PAGE、实验感染、“ABC”组化抗原定位等证实病原为MRV,而且病毒大小、RNA电泳型与国外...本文研究了1986—1989年间BALB/C小鼠发生的两次散发流行和一次有BALB/C及NIH鼠群暴发流行的EDIM(Epizootic diarrhea of infant mice)。经过电镜、PAGE、实验感染、“ABC”组化抗原定位等证实病原为MRV,而且病毒大小、RNA电泳型与国外报道的MRV有差异。观察了本繁育场内7个品系小鼠,均查出有MRV抗体,但发病只见于BALB/C和NIH鼠群。不同鼠龄和胎次发病率亦有差异。还观察了病变组织的病理组织学,扫描电镜和超微结构的改变。展开更多
文摘For electronic microscopic observation, we found SSV-transformed NIH 3T3 cells were different from non-transformed cells. In SSV-transformed NIH 3T3 cells nuclei cytoplasma ratio was increased and in cytoplasma the ribosomes (polyribosomes were attached to the swollen rough endoplasmic reticulum. It was likely that ribosomes were lined together functionally and structionally to produce specific protein (PDGF-like protein).
文摘A well-known Chinese traditional drug, decoction of wick of sun-flower stem, has been used to treat cancer and certain other diseases.1,2 Animal experiments in mice showed that transplantation of Sarcoma 180 (S180) and of Uterus cervical cancer 14 (U14) were signlflcanly inhibited by this decoction. The Inhibition rates of tumor weight were 33 -81 % and in about 6 - 20% of treated mice, complete tumor regression has been demonstrated. So tar no acute toxic side-effect was noted. This is in contrast to most of the antitumor chemltherapeutic drugs known to produce different degrees of toxlcity or induce Immunosuppression as a side effect. For this reason, we have undertaken the present study.
文摘本文研究了1986—1989年间BALB/C小鼠发生的两次散发流行和一次有BALB/C及NIH鼠群暴发流行的EDIM(Epizootic diarrhea of infant mice)。经过电镜、PAGE、实验感染、“ABC”组化抗原定位等证实病原为MRV,而且病毒大小、RNA电泳型与国外报道的MRV有差异。观察了本繁育场内7个品系小鼠,均查出有MRV抗体,但发病只见于BALB/C和NIH鼠群。不同鼠龄和胎次发病率亦有差异。还观察了病变组织的病理组织学,扫描电镜和超微结构的改变。
