PtX 2 ],and alkaline earth cations malonate or ammonium malonate were applied in t he synthesis.The re-sulting platinum(Ⅱ)complex has been characterized with its IR,1 H-NMR and 13 C-NMR,FAB-MS and TG-DTA spectra.
N (Trans 4 isopropylcyclohexyl 1 carbonyl) D phenylalanine,nateglide,is an effective drug to decrease blood sugar,which is under clinical trials in China.This compound has been reported to have two crystal types,of wh...N (Trans 4 isopropylcyclohexyl 1 carbonyl) D phenylalanine,nateglide,is an effective drug to decrease blood sugar,which is under clinical trials in China.This compound has been reported to have two crystal types,of which the one is more suitable to prebare the drug.We have studied the preparation of different crystal types and discovered a new one that has not been reported in the literature.Their melting points,TGA DTA and DSC spectral data,IR and X ray powder diffraction spectra of all samples have been investigated with different crystal types,some have been compared with the commercial drug from abroad.Suggestions have been made to control the crystal type.展开更多
complex[Ni(La) 2 ](NO 3 )2 (1)with bidentate racemic1,2,2-trimethylcyclopentane-1,3-diamine lig-and has been synthesized and characterized by IR,EA,ES-MS,and its X-ray diffracti on study reveals that the nickel (Ⅱ)ab...complex[Ni(La) 2 ](NO 3 )2 (1)with bidentate racemic1,2,2-trimethylcyclopentane-1,3-diamine lig-and has been synthesized and characterized by IR,EA,ES-MS,and its X-ray diffracti on study reveals that the nickel (Ⅱ)abstract: center is tetra-coordinated by one D-and one L-diamine ligands,and a thre e-dimensional hydrogen-bond-sustained network is formed in the solid state by means of the eight-membered N-H...O hydrogen bond cy-cle.This compound also su pplies a good comparison to the chiral complex[Ni(L b )2 ]Cl 2 ·2H 2 O(2)(L b =D-(+)abstract:-1,2,2-trimethylcyclopentane-1,3-diamine)abstract:.CCDC:218122.展开更多
文摘PtX 2 ],and alkaline earth cations malonate or ammonium malonate were applied in t he synthesis.The re-sulting platinum(Ⅱ)complex has been characterized with its IR,1 H-NMR and 13 C-NMR,FAB-MS and TG-DTA spectra.
文摘N (Trans 4 isopropylcyclohexyl 1 carbonyl) D phenylalanine,nateglide,is an effective drug to decrease blood sugar,which is under clinical trials in China.This compound has been reported to have two crystal types,of which the one is more suitable to prebare the drug.We have studied the preparation of different crystal types and discovered a new one that has not been reported in the literature.Their melting points,TGA DTA and DSC spectral data,IR and X ray powder diffraction spectra of all samples have been investigated with different crystal types,some have been compared with the commercial drug from abroad.Suggestions have been made to control the crystal type.
文摘complex[Ni(La) 2 ](NO 3 )2 (1)with bidentate racemic1,2,2-trimethylcyclopentane-1,3-diamine lig-and has been synthesized and characterized by IR,EA,ES-MS,and its X-ray diffracti on study reveals that the nickel (Ⅱ)abstract: center is tetra-coordinated by one D-and one L-diamine ligands,and a thre e-dimensional hydrogen-bond-sustained network is formed in the solid state by means of the eight-membered N-H...O hydrogen bond cy-cle.This compound also su pplies a good comparison to the chiral complex[Ni(L b )2 ]Cl 2 ·2H 2 O(2)(L b =D-(+)abstract:-1,2,2-trimethylcyclopentane-1,3-diamine)abstract:.CCDC:218122.
