口腔数字化诊疗技术指借助数字化扫描、诊断、设计与制造、临床手术治疗等技术手段实现口腔疾病诊疗的一系列技术。口腔数字化诊疗技术融合了三维数据采集技术、数学建模技术、计算机辅助设计与增材制造技术(C A D/C A M和3D打印)、机...口腔数字化诊疗技术指借助数字化扫描、诊断、设计与制造、临床手术治疗等技术手段实现口腔疾病诊疗的一系列技术。口腔数字化诊疗技术融合了三维数据采集技术、数学建模技术、计算机辅助设计与增材制造技术(C A D/C A M和3D打印)、机器人技术、人工智能技术、手术导航技术及相关材料技术,展示了令人振奋的应用场景:患者数据能够更加容易而精确的获取、存储和共享,在医疗机构、技工室、加工中心、设备和材料及软件提供商、第三方服务机构等关联方之间实现非线性、安全可控的流动,使得从数据获取、三维重建、打印或切削加工、贴面和修整、临床治疗完成等全流程和包括美容、诊疗、预防等全产业链条更加微创、精确、高效和智能化。展开更多
1银汞合金的发展历程作为永久性口腔充填修复材料,银汞合金已有千余年的历史。世界上汞合金用于口腔修复的最早记载考追溯到公元659年,我国唐代苏敬(苏恭)等著《新修本草》(《唐本草》)中记载了银膏用以补牙'以白锡和银薄及水银合成...1银汞合金的发展历程作为永久性口腔充填修复材料,银汞合金已有千余年的历史。世界上汞合金用于口腔修复的最早记载考追溯到公元659年,我国唐代苏敬(苏恭)等著《新修本草》(《唐本草》)中记载了银膏用以补牙'以白锡和银薄及水银合成之';1578年,明朝李时珍所著的《本草纲目》进行了更为详细的描述;19世纪之后,巴黎医生Louis Nicolas Regnart将10%的汞加入熔融合金形成软化合金并在室温固化用于填充物.展开更多
The influence of different pH values between assembly and application environment on the surface properties of layer-by-layer assembled heparin and chitosan multilayer films was investigated.The high adsorption amount...The influence of different pH values between assembly and application environment on the surface properties of layer-by-layer assembled heparin and chitosan multilayer films was investigated.The high adsorption amount of cationic dye and high wettability on the chitosan terminated multilayer films at high environment pH may indicate the excess of free sulfate group existed on the chitosan surface.Since the ionization degree of chitosan decreased with increasing of pH,the multilayer films assembled at low pH will lead to some excess free unpaired sulfate group in higher pH application environment,which paired with ionized amino group under prepared conditions.The blood-compatibility tests performed with these films clearly demonstrated that the good anticoagulant activity of low pH assembled heparin/chitosan even on the chitosan-terminated surface.Such an easy and controlled processing by the difference of pH values between assembly and application environment may have a good potential for fabrication of biomedical device coating.展开更多
A novel bioinspired phospholipid copolymer was synthesized by the free radical polymerization of poly-2-methacryloyloxyethylphosphorylcholine(MPC), stearyl methacrylate(SMA), hydroxypropyl methacrylate(HPMA) and trime...A novel bioinspired phospholipid copolymer was synthesized by the free radical polymerization of poly-2-methacryloyloxyethylphosphorylcholine(MPC), stearyl methacrylate(SMA), hydroxypropyl methacrylate(HPMA) and trimethoxysilylpropyl methacrylate(TSMA). A stable cross-linked coating was obtained via dip-coating, followed by curing at 70 ℃ for 9 h. Contact angle results indicate the coating surface rearrange to get a more hydrophilic surface on the polymer/water interface. The membrane mimic phosphorylcholine coating surface can resist the platelet adhesion and prolong plasma recalcification time significantly. Rhodamine S was used as model drugs to prepare drug-containing coating under the same conditions. Drug-releasing curves fall into Fickian release mechanism and there exists an efficient releasing-amount of the drug until 60 h.展开更多
文摘口腔数字化诊疗技术指借助数字化扫描、诊断、设计与制造、临床手术治疗等技术手段实现口腔疾病诊疗的一系列技术。口腔数字化诊疗技术融合了三维数据采集技术、数学建模技术、计算机辅助设计与增材制造技术(C A D/C A M和3D打印)、机器人技术、人工智能技术、手术导航技术及相关材料技术,展示了令人振奋的应用场景:患者数据能够更加容易而精确的获取、存储和共享,在医疗机构、技工室、加工中心、设备和材料及软件提供商、第三方服务机构等关联方之间实现非线性、安全可控的流动,使得从数据获取、三维重建、打印或切削加工、贴面和修整、临床治疗完成等全流程和包括美容、诊疗、预防等全产业链条更加微创、精确、高效和智能化。
文摘1银汞合金的发展历程作为永久性口腔充填修复材料,银汞合金已有千余年的历史。世界上汞合金用于口腔修复的最早记载考追溯到公元659年,我国唐代苏敬(苏恭)等著《新修本草》(《唐本草》)中记载了银膏用以补牙'以白锡和银薄及水银合成之';1578年,明朝李时珍所著的《本草纲目》进行了更为详细的描述;19世纪之后,巴黎医生Louis Nicolas Regnart将10%的汞加入熔融合金形成软化合金并在室温固化用于填充物.
文摘The influence of different pH values between assembly and application environment on the surface properties of layer-by-layer assembled heparin and chitosan multilayer films was investigated.The high adsorption amount of cationic dye and high wettability on the chitosan terminated multilayer films at high environment pH may indicate the excess of free sulfate group existed on the chitosan surface.Since the ionization degree of chitosan decreased with increasing of pH,the multilayer films assembled at low pH will lead to some excess free unpaired sulfate group in higher pH application environment,which paired with ionized amino group under prepared conditions.The blood-compatibility tests performed with these films clearly demonstrated that the good anticoagulant activity of low pH assembled heparin/chitosan even on the chitosan-terminated surface.Such an easy and controlled processing by the difference of pH values between assembly and application environment may have a good potential for fabrication of biomedical device coating.
文摘A novel bioinspired phospholipid copolymer was synthesized by the free radical polymerization of poly-2-methacryloyloxyethylphosphorylcholine(MPC), stearyl methacrylate(SMA), hydroxypropyl methacrylate(HPMA) and trimethoxysilylpropyl methacrylate(TSMA). A stable cross-linked coating was obtained via dip-coating, followed by curing at 70 ℃ for 9 h. Contact angle results indicate the coating surface rearrange to get a more hydrophilic surface on the polymer/water interface. The membrane mimic phosphorylcholine coating surface can resist the platelet adhesion and prolong plasma recalcification time significantly. Rhodamine S was used as model drugs to prepare drug-containing coating under the same conditions. Drug-releasing curves fall into Fickian release mechanism and there exists an efficient releasing-amount of the drug until 60 h.
