A 51-year-old man was hospitalized with severe pain on waist and limitation of movement for one hour. He was diagnosed as compression fracture on lumbar vertebrae 1, and treated with intravenous infusion of sodium aes...A 51-year-old man was hospitalized with severe pain on waist and limitation of movement for one hour. He was diagnosed as compression fracture on lumbar vertebrae 1, and treated with intravenous infusion of sodium aescinate 10mg daily. The patient developed fever, sweat, nausea, fatigue, anorexia, yellowing of sclera and the skin after receiving the medication. Physical examination showed tenderness on right upper abdomen and percussion pain on both renal areas. Lab findings showed ALT 753U/L, T-Bil 80.1μmol / L and BUN 19.44mmo / L. It was considered to be drug-induced hepatorenal impairment. Sodium aescinate was then withdrawn. 10 days later his conditions were returned to normal.展开更多
文摘A 51-year-old man was hospitalized with severe pain on waist and limitation of movement for one hour. He was diagnosed as compression fracture on lumbar vertebrae 1, and treated with intravenous infusion of sodium aescinate 10mg daily. The patient developed fever, sweat, nausea, fatigue, anorexia, yellowing of sclera and the skin after receiving the medication. Physical examination showed tenderness on right upper abdomen and percussion pain on both renal areas. Lab findings showed ALT 753U/L, T-Bil 80.1μmol / L and BUN 19.44mmo / L. It was considered to be drug-induced hepatorenal impairment. Sodium aescinate was then withdrawn. 10 days later his conditions were returned to normal.
