A new three-dimensional Zn（II） coordination polymer, namely [Zn4（bpydb）3（tz）2（H2O）2]n（1）, has been synthesized by the self-assembly reactions of Zn（NO3）2·6H2O, bpydb H2, Htz and DMF. Single-crystal X-...A new three-dimensional Zn（II） coordination polymer, namely [Zn4（bpydb）3（tz）2（H2O）2]n（1）, has been synthesized by the self-assembly reactions of Zn（NO3）2·6H2O, bpydb H2, Htz and DMF. Single-crystal X-ray structural analysis reveals that compound 1 features a three-dimensional framework structure and is the first example of Zn-containing coordination polymers based on two kinds of ligands bpydb H2 and Htz. It crystallizes in triclinic, space group P1 with a = 14.9953（12）, b = 17.5335（17）, c = 20.2381（11）A, α = 115.225（7）, β = 92.329（5）, γ = 105.606（8）o, V = 4561.9（7） A^3, Z = 2, F（000） = 1644, Dc = 1.177 Mg/m^3, Mr = 1616.76 and μ = 1.098 mm^-1. The antitumor activities of compound 1 and its corresponding organic ligands（bpydb H2 and Htz） were investigated for inhibiting human osteosarcoma cells（MG-63 and U-2 OS） growth by MTT assay. It was found that compared with the two ligands, compound 1 exerted rather potent activities against all of these cell lines.展开更多
[目的]观察人工髋关节置换术(artificial hip replacement)与动力髋螺钉(dynamic hip screw,DHS)内固定治疗高龄股骨粗隆间骨折的临床疗效。[方法]选择本院2007年6月～2011年2月收治的高龄股骨粗隆间骨折患者60例,依据随机对照原则分为...[目的]观察人工髋关节置换术(artificial hip replacement)与动力髋螺钉(dynamic hip screw,DHS)内固定治疗高龄股骨粗隆间骨折的临床疗效。[方法]选择本院2007年6月～2011年2月收治的高龄股骨粗隆间骨折患者60例,依据随机对照原则分为关节置换组(30例)与DHS内固定组(30例),观察并比较两组患者的手术时间、术中输血量、术后卧床时间、术后关节评分及术后并发症发生情况。[结果]所有患者均获随访,随访时间16～29个月,平均24.1个月。关节置换组在手术时间、术中出血量及术后卧床时间低于内固定组,其差异具有显著的统计学意义(P<0.05);关节置换组术后并发症的发生率为16.7%(5/30),内固定组术后并发症的发生率为43.3%(13/30),关于置换组的术后并发症的发生率低于内固定组,其差异具有显著的统计学意义(P<0.05);关节置换组Harris评分差值高于内固定组,其差异具有显著的统计学意义(P<0.05)。[结论]对于高龄股骨粗隆间骨折的患者,采用人工髋关节置换术较动力髋螺钉治疗疗效更为可靠。展开更多
文摘A new three-dimensional Zn（II） coordination polymer, namely [Zn4（bpydb）3（tz）2（H2O）2]n（1）, has been synthesized by the self-assembly reactions of Zn（NO3）2·6H2O, bpydb H2, Htz and DMF. Single-crystal X-ray structural analysis reveals that compound 1 features a three-dimensional framework structure and is the first example of Zn-containing coordination polymers based on two kinds of ligands bpydb H2 and Htz. It crystallizes in triclinic, space group P1 with a = 14.9953（12）, b = 17.5335（17）, c = 20.2381（11）A, α = 115.225（7）, β = 92.329（5）, γ = 105.606（8）o, V = 4561.9（7） A^3, Z = 2, F（000） = 1644, Dc = 1.177 Mg/m^3, Mr = 1616.76 and μ = 1.098 mm^-1. The antitumor activities of compound 1 and its corresponding organic ligands（bpydb H2 and Htz） were investigated for inhibiting human osteosarcoma cells（MG-63 and U-2 OS） growth by MTT assay. It was found that compared with the two ligands, compound 1 exerted rather potent activities against all of these cell lines.
文摘[目的]观察人工髋关节置换术(artificial hip replacement)与动力髋螺钉(dynamic hip screw,DHS)内固定治疗高龄股骨粗隆间骨折的临床疗效。[方法]选择本院2007年6月～2011年2月收治的高龄股骨粗隆间骨折患者60例,依据随机对照原则分为关节置换组(30例)与DHS内固定组(30例),观察并比较两组患者的手术时间、术中输血量、术后卧床时间、术后关节评分及术后并发症发生情况。[结果]所有患者均获随访,随访时间16～29个月,平均24.1个月。关节置换组在手术时间、术中出血量及术后卧床时间低于内固定组,其差异具有显著的统计学意义(P<0.05);关节置换组术后并发症的发生率为16.7%(5/30),内固定组术后并发症的发生率为43.3%(13/30),关于置换组的术后并发症的发生率低于内固定组,其差异具有显著的统计学意义(P<0.05);关节置换组Harris评分差值高于内固定组,其差异具有显著的统计学意义(P<0.05)。[结论]对于高龄股骨粗隆间骨折的患者,采用人工髋关节置换术较动力髋螺钉治疗疗效更为可靠。
