含葛根素冷钾停搏液对低温全心缺血心肌保护作用的电镜观察

采用低温体外循环下原位犬动物实验模型,用电镜观察和比较冷钾停搏液和添加葛根素的冷钾停搏液灌注后,停搏140 min全心缺血心肌的超微结构变化。结果显示:含葛根素心脏停搏液对心肌的超微结构具有良好的保护作用。

KA8肽对酒精所致大鼠胃粘膜损伤的保护作用

采用经胃管给禁食大鼠注入１ｍＬ纯酒精造成胃粘膜损伤的方法，观察预先给予ＫＡ８肽对胃粘膜的保护作用，实验结果表明，注入１ｍＬ纯酒精１ｈ后，大鼠胃粘膜损伤严重，面积广泛。皮下注射ＫＡ８肽３０、６０μｇ／ｋｇ体重均可使酒精所致大鼠胃粘膜损伤明显减轻，损伤面积较对照组明显减少（Ｐ＜０．０１）。由此推断，ＫＡ８肽对胃粘膜具有细胞保护作用。

ADDISON'S DISEASE OF AUTOSOMAL DOMINANT INHERITANCE——A REPORT OF 11 CASES IN ONE FAMILY

Congenital Addison’s disease due to autosomal dominant inheritance has not been reported in domestic and foreign literature yet. In this note, 11 cases of congenital Addison’s diseases among 66 persons in one family due to autosomal dominant inheritance are first reported and the etiology of this disease is discussed.