Nine Mannich base derivatives of thymol are synthesized,the yield is compared between common(50～55℃) and ultrasonic radiation(rt) condition.All the target compounds have been identified by elemental analysis,IR and ...Nine Mannich base derivatives of thymol are synthesized,the yield is compared between common(50～55℃) and ultrasonic radiation(rt) condition.All the target compounds have been identified by elemental analysis,IR and 1HNMR spectra.The characteristic of these reaction are simple process,mild condition,and good yields(42-79%).The alkyl amine derivatives show weak antiblastic activity,the heterocyclic amine derivatives show antiblastic activity.展开更多
文摘Nine Mannich base derivatives of thymol are synthesized,the yield is compared between common(50～55℃) and ultrasonic radiation(rt) condition.All the target compounds have been identified by elemental analysis,IR and 1HNMR spectra.The characteristic of these reaction are simple process,mild condition,and good yields(42-79%).The alkyl amine derivatives show weak antiblastic activity,the heterocyclic amine derivatives show antiblastic activity.
