中医药防治老年痴呆的研究进展

Senile Dementia has become more frequent with increasing life expectancy. It is severely threatening our aging society. De- mentia is characterized by progressive memory loss, associated with agnosia, dyscalculia, apraxia, and deficits in executive functioning. Alzheimer’ s disease is the most frequent cause of dementia. Up till now, it has been left doctors helpless to halt its unavoidable progress. The drugs, which have been approved by FDA for the symptomatic management of AD, are far from ideal. Therefore, more and more researchers have been putting theirs eyes on he rbal medicine. TCM has a goodeffect onsenile dementia.This paper summarizes theprogress ofTCM on senile dementia in some aspects, including guidance on clinical investigation of medical products for the treatment of Alzheimer’s disease, animal models, Traditional Chinese Medi- cine and its active ingredients, Prescriptions of TCM etc. It is hoped that this knowledge will benefit for prevention and treatment Dementia. [

口炎清颗粒中绿原酸HPLC测定及其稳定性考察

目的 建立口炎清颗粒中绿原酸的含量测定方法及考察其稳定性。方法 以依利特 C1 8柱为分析柱 ,乙腈 - 0 .4 %磷酸 (90∶ 10 )为流动相 ,流速 1.0 m L / m in,32 7nm为检测波长 ,对口炎清颗粒中的绿原酸含量进行了 HPL C测定 ,并对储藏过程中绿原酸的稳定性进行了考察。结果 该含量测定方法操作简单、重复性好 ,回收率达 99%以上 ,口炎清颗粒中绿原酸在 18个月内保持相对稳定。结论 本文 HPL C方法稳定可靠 。