The title compounds(7a^7g)were synthesized from dehydroabietic acid and characterized by spectroscopic methods including HR-MS,1H-and 13C-NMR.The crystal structure of compound 7g determined by single-crystal X-ray dif...The title compounds(7a^7g)were synthesized from dehydroabietic acid and characterized by spectroscopic methods including HR-MS,1H-and 13C-NMR.The crystal structure of compound 7g determined by single-crystal X-ray diffractio is of monoclinic system,space group P21 with a=12.282(3),b=9.940(2),c=22.656(5)A,β=103.06(3)°,Z=2,V=2694.4(10)A^3,Mr=1182.95,Dc=1.458 Mg/m^3,S=1.000,μ=1.649 mm^-1,F(000)=1216,the final R=0.0791 and wR=0.1853 for 4098 observed reflections(Ⅰ>2σ(Ⅰ)).The preliminary antibacterial assay showed that compound 7g exhibits significant inhibitory against Bacillus subtilis,Staphylococcus aureus and Methicillin-resistant S.aureus(MRSA)with MIC values of 1.9~7.8μg/mL.展开更多
Two Schiff bases(DAMBA-Fc and DAA-Fc)derived from dehydroabietic acid have been successfully synthesized and characterized by means of FT-IR,elemental analysis,HRMS,and NMR spectroscopy.The crystal structure of DAA-Fc...Two Schiff bases(DAMBA-Fc and DAA-Fc)derived from dehydroabietic acid have been successfully synthesized and characterized by means of FT-IR,elemental analysis,HRMS,and NMR spectroscopy.The crystal structure of DAA-Fc can be determined by single-crystal X-ray diffraction.The compound is of monoclinic system,space group P21 with a=10.7379(6),b=7.5004(4),c=33.3294(18)?,β=97.996(3)o,Z=4,V=2658.2(3)?3,Mr=481.48,Dc=1.203 g/cm3,S=1.034,μ=0.585 mm-1,F(000)=1032,the final R=0.0566 and wR=0.0701 for 5645 observed reflections(I>2σ(I)).In addition,cyclic and differential pulse voltammogram techniques have been applied to differentiate the redox properties of the aromatic-and aliphatic-connected Schiff bases DAMBA-Fc and DAA-Fc,respectively.展开更多
基金supported by the National Natural Science Foundation of China(31770616 and 21601087)the Natural Science Foundation for Colleges and Universities in Jiangsu Province(17KJA220002)Top-notch Academic Programs Project of Jiangsu Higher Education Institutions(PPZY2015C221)。
文摘The title compounds(7a^7g)were synthesized from dehydroabietic acid and characterized by spectroscopic methods including HR-MS,1H-and 13C-NMR.The crystal structure of compound 7g determined by single-crystal X-ray diffractio is of monoclinic system,space group P21 with a=12.282(3),b=9.940(2),c=22.656(5)A,β=103.06(3)°,Z=2,V=2694.4(10)A^3,Mr=1182.95,Dc=1.458 Mg/m^3,S=1.000,μ=1.649 mm^-1,F(000)=1216,the final R=0.0791 and wR=0.1853 for 4098 observed reflections(Ⅰ>2σ(Ⅰ)).The preliminary antibacterial assay showed that compound 7g exhibits significant inhibitory against Bacillus subtilis,Staphylococcus aureus and Methicillin-resistant S.aureus(MRSA)with MIC values of 1.9~7.8μg/mL.
基金Supported by the National Natural Science Foundation of China(21601087 and 21401101)the Topnotch Academic Programs Project(TAPP)the Priority Academic Program Development of Jiangsu Higher Education Institution(PAPD)。
文摘Two Schiff bases(DAMBA-Fc and DAA-Fc)derived from dehydroabietic acid have been successfully synthesized and characterized by means of FT-IR,elemental analysis,HRMS,and NMR spectroscopy.The crystal structure of DAA-Fc can be determined by single-crystal X-ray diffraction.The compound is of monoclinic system,space group P21 with a=10.7379(6),b=7.5004(4),c=33.3294(18)?,β=97.996(3)o,Z=4,V=2658.2(3)?3,Mr=481.48,Dc=1.203 g/cm3,S=1.034,μ=0.585 mm-1,F(000)=1032,the final R=0.0566 and wR=0.0701 for 5645 observed reflections(I>2σ(I)).In addition,cyclic and differential pulse voltammogram techniques have been applied to differentiate the redox properties of the aromatic-and aliphatic-connected Schiff bases DAMBA-Fc and DAA-Fc,respectively.
