The title compound 2-oxo-3-phenyl-1-oxaspiro[4.5]dec-3-en-4-yl 4-chlorobenzoate 6 （C22H19ClO4, Mr = 382.82） has been synthesized by the condensation reaction of 4-hydroxy-3-phenyl-1-oxaspiro[4.5]dec-3-en-2-one 5 wit...The title compound 2-oxo-3-phenyl-1-oxaspiro[4.5]dec-3-en-4-yl 4-chlorobenzoate 6 （C22H19ClO4, Mr = 382.82） has been synthesized by the condensation reaction of 4-hydroxy-3-phenyl-1-oxaspiro[4.5]dec-3-en-2-one 5 with 4-chlorobenzoyl chloride, and its crystal structure was determined by single-crystal X-ray diffraction. The crystal belongs to the monoclinic system, space group P21/n with a = 10.6749（11）, b = 6.0573（7）, c = 29.680（2） A, β = 94.073（3）°, V= 1914.3（3） A^3, Z = 4, Dc = 1.328 g/cm^3, F（000） = 800, μ = 0.224 mm^-1, S = 1.003, the final R = 0.0605 and wR = 0.1500 for 1828 observed reflections with I〉 2σ（I） and 244 variable parameters. The crystal analysis shows that the molecular structure of the title compound has one planar furan ring, one chair conformation cyclohexane ring and two benzene rings. The furan and cyclohexane rings adopt whorl conformations.展开更多
基金Supported by the National Natural Science Foundation of China (Nos. 31101470 and 30700532)
文摘The title compound 2-oxo-3-phenyl-1-oxaspiro[4.5]dec-3-en-4-yl 4-chlorobenzoate 6 （C22H19ClO4, Mr = 382.82） has been synthesized by the condensation reaction of 4-hydroxy-3-phenyl-1-oxaspiro[4.5]dec-3-en-2-one 5 with 4-chlorobenzoyl chloride, and its crystal structure was determined by single-crystal X-ray diffraction. The crystal belongs to the monoclinic system, space group P21/n with a = 10.6749（11）, b = 6.0573（7）, c = 29.680（2） A, β = 94.073（3）°, V= 1914.3（3） A^3, Z = 4, Dc = 1.328 g/cm^3, F（000） = 800, μ = 0.224 mm^-1, S = 1.003, the final R = 0.0605 and wR = 0.1500 for 1828 observed reflections with I〉 2σ（I） and 244 variable parameters. The crystal analysis shows that the molecular structure of the title compound has one planar furan ring, one chair conformation cyclohexane ring and two benzene rings. The furan and cyclohexane rings adopt whorl conformations.
