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Induction of Rat Prolactinoma by β-Estradiol and Its Relation to Expression of c-myc Oncogene
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作者 许荣琨 郭传海 +4 位作者 黄曼影 韩小四 周远征 单惠敏 黄醒亚 《Developmental and Reproductive Biology》 1995年第1期64-69,T001-T002,共8页
Sprague-Dawley rats were implanted with silastic capsules containing β-estradiol. After 60 days, their pituitary weights, serum prolactin contentsand transcription level of c-myc proto-oncogene were found increasedsi... Sprague-Dawley rats were implanted with silastic capsules containing β-estradiol. After 60 days, their pituitary weights, serum prolactin contentsand transcription level of c-myc proto-oncogene were found increasedsignificantly. It was also found that the anterior pituitary cells proliferatedsignificantly, but their differentiation was suppressed. 展开更多
关键词 ESTRADIOL Anterior pituitary tumor PROLACTIN PROTOONCOGENE
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