目的:通过对便通胶囊健脾固本的药效学研究,揭示其疗效特点的内在机制。方法:将小鼠分成不同剂量的便通胶囊组、空白对照组(生理盐水)和阳性对照组(黄芪或麻仁丸),观察便通胶囊对小鼠淋巴细胞转化率、溶血素抗体水平、NK 细胞活性及胸...目的:通过对便通胶囊健脾固本的药效学研究,揭示其疗效特点的内在机制。方法:将小鼠分成不同剂量的便通胶囊组、空白对照组(生理盐水)和阳性对照组(黄芪或麻仁丸),观察便通胶囊对小鼠淋巴细胞转化率、溶血素抗体水平、NK 细胞活性及胸腺指数的影响;对耐乏氧和耐疲劳的影响;对不同肠段水分含量的影响。结果:便通胶囊能提高小鼠淋巴细胞转化率、促进溶血素抗体的形成,增强 NK 细胞活性,提高胸腺指标,提高小鼠耐乏氧和耐疲劳能力,对小肠水分吸收无影响。结论:改善免疫功能,提高体能和适应能力及对小肠段水分吸收的作用特点,构成了便通胶囊健脾固本的主要药效学内涵,而健脾固本保证了本药通而不泻,下不伤正疗效特点实现。展开更多
140 cases of epigastralgia were divided into two groups at random. The 100 cases in thetreatment group were treated with Huweigao externally applied at Shenque (Ren 8), andthe 40 cases in the control group by oral adm...140 cases of epigastralgia were divided into two groups at random. The 100 cases in thetreatment group were treated with Huweigao externally applied at Shenque (Ren 8), andthe 40 cases in the control group by oral administration of Weinaian capsule. After a one-month treatment, the total symptom-relieving rate and the gastroscopy-proved effectiverate were 94.0% and 52.6% respectively in the treatment group, much superior to thosein the control group.展开更多
文摘目的:通过对便通胶囊健脾固本的药效学研究,揭示其疗效特点的内在机制。方法:将小鼠分成不同剂量的便通胶囊组、空白对照组(生理盐水)和阳性对照组(黄芪或麻仁丸),观察便通胶囊对小鼠淋巴细胞转化率、溶血素抗体水平、NK 细胞活性及胸腺指数的影响;对耐乏氧和耐疲劳的影响;对不同肠段水分含量的影响。结果:便通胶囊能提高小鼠淋巴细胞转化率、促进溶血素抗体的形成,增强 NK 细胞活性,提高胸腺指标,提高小鼠耐乏氧和耐疲劳能力,对小肠水分吸收无影响。结论:改善免疫功能,提高体能和适应能力及对小肠段水分吸收的作用特点,构成了便通胶囊健脾固本的主要药效学内涵,而健脾固本保证了本药通而不泻,下不伤正疗效特点实现。
文摘140 cases of epigastralgia were divided into two groups at random. The 100 cases in thetreatment group were treated with Huweigao externally applied at Shenque (Ren 8), andthe 40 cases in the control group by oral administration of Weinaian capsule. After a one-month treatment, the total symptom-relieving rate and the gastroscopy-proved effectiverate were 94.0% and 52.6% respectively in the treatment group, much superior to thosein the control group.
