We study the feasibility and safety of human lung hyperpolarized（HP）^（129）Xe magnetic resonance imaging（MRI）.There is no significant change in physiological parameters before and after the examinations of all su...We study the feasibility and safety of human lung hyperpolarized（HP）^（129）Xe magnetic resonance imaging（MRI）.There is no significant change in physiological parameters before and after the examinations of all subjects.Compared with computed tomography, HP^（129）Xe MRI is sensitive to earlier and smaller ventilation defects. The distribution of the HP^（129）Xe MRI signal reflects the pulmonary compliance with the gravity gradient. This is the first application of HP^（129）Xe MRI ventilation imaging in China, and this technology is expected to provide more useful information for clinical practice.展开更多
基金Supported by the National Natural Science Foundation of China under Grant Nos 81227902 and 81625011the National Key Research and Development Program of China under Grant No 2016YFC1304702the Key Research Program of Frontier Sciences of CAS(QYZDY-SSW-SLH018)
文摘We study the feasibility and safety of human lung hyperpolarized（HP）^（129）Xe magnetic resonance imaging（MRI）.There is no significant change in physiological parameters before and after the examinations of all subjects.Compared with computed tomography, HP^（129）Xe MRI is sensitive to earlier and smaller ventilation defects. The distribution of the HP^（129）Xe MRI signal reflects the pulmonary compliance with the gravity gradient. This is the first application of HP^（129）Xe MRI ventilation imaging in China, and this technology is expected to provide more useful information for clinical practice.
