Plant cyclopeptides, cyclic compounds formed mainly by the peptidic bonds of 2--37 protein and non-protein amino acids （mainly L-amino acids） and found in higher plants, have been attractive for their extensive bioa...Plant cyclopeptides, cyclic compounds formed mainly by the peptidic bonds of 2--37 protein and non-protein amino acids （mainly L-amino acids） and found in higher plants, have been attractive for their extensive bioactivities and distinctive molecular architectures. During the last half century＇s study, about 500 cyclopeptides divided into eight types have been isolated from over 120 species, which belong to over 20 families and 60 genera. Some cyclopeptides showed potential anti-tumor, sedative, immunosuppressive, and uterotonic activities. In the Chinese Pharmacopoeia （CP, 2010 Version）, 23 species （14 families, 18 genera） containing cyclopeptides have been re- corded in the origins of 24 traditional Chinese medicines （TCMs）. Heterophyllin B （64）, first reported by us from Pseudostellaria heterophylla in 1993 was cited for the first time in CP as the standard substance of cyclopeptides for quality control. In this review, we highlight the progress in the chemical studies of these cyclopeptide-containing TCMs, in particular recent results in our group＇s publications.展开更多
文摘传统的卷积神经网络需要大量的运算单元和繁琐的数据存取,导致计算速度较慢,效率不高.本文设计了全新的数据块结构以充分利用数据复用,大大减少数据读取次数,并且全面调用FPGA的并行运算资源,同时进行多个乘加操作,实现了高效并行卷积计算电路.将权重和偏置参数分别融合、最优化量化,减少了内存占用.通过以VGG16作为测试网络,在识别Imagenet数据集时,精度仅损失了0.02%,在200 MHz的情况下,吞吐率达到了129.6 GOPS,功耗仅为5.26 W.
文摘Plant cyclopeptides, cyclic compounds formed mainly by the peptidic bonds of 2--37 protein and non-protein amino acids （mainly L-amino acids） and found in higher plants, have been attractive for their extensive bioactivities and distinctive molecular architectures. During the last half century＇s study, about 500 cyclopeptides divided into eight types have been isolated from over 120 species, which belong to over 20 families and 60 genera. Some cyclopeptides showed potential anti-tumor, sedative, immunosuppressive, and uterotonic activities. In the Chinese Pharmacopoeia （CP, 2010 Version）, 23 species （14 families, 18 genera） containing cyclopeptides have been re- corded in the origins of 24 traditional Chinese medicines （TCMs）. Heterophyllin B （64）, first reported by us from Pseudostellaria heterophylla in 1993 was cited for the first time in CP as the standard substance of cyclopeptides for quality control. In this review, we highlight the progress in the chemical studies of these cyclopeptide-containing TCMs, in particular recent results in our group＇s publications.
