微型反向重复转座元件(MITEs)是一类短的非自主DNA转座子,其分布的位置会对宿主产生影响。文章使用生物信息学的方法对无颌类、软骨鱼纲、肉鳍鱼纲和辐鳍鱼纲鱼类基因组进行了MITEs预测,最终在33种鱼类基因组中鉴定出2433个M I T E s家...微型反向重复转座元件(MITEs)是一类短的非自主DNA转座子,其分布的位置会对宿主产生影响。文章使用生物信息学的方法对无颌类、软骨鱼纲、肉鳍鱼纲和辐鳍鱼纲鱼类基因组进行了MITEs预测,最终在33种鱼类基因组中鉴定出2433个M I T E s家族。文章发现鱼类基因组中M I T E s含量存在较大差异(0.11%—21.18%),并且MITEs含量与鱼类基因组大小呈正相关关系。根据末端重复序列(TIRs)和靶位点重复序列(TSDs)的特征将MITEs分为10个超家族,其中TC1-Mariner超家族的含量最高。MITEs在鱼类基因组中的插入事件主要发生在4百万年前至今,大多数物种的MITEs在2百万—0.5百万年前发生了爆发式扩增。鱼类基因组中的MITEs多数插入到基因内部或附近,这些转座子可能在基因的表达调控方面存在重要作用。展开更多
For purpose of a more comprehensive understanding of the flow in the disk cavities, the sealing flow in both the upstream and downstream disk-cavity system of a 1.5 stage turbine is investigated by means of CFD method...For purpose of a more comprehensive understanding of the flow in the disk cavities, the sealing flow in both the upstream and downstream disk-cavity system of a 1.5 stage turbine is investigated by means of CFD methods.The result indicates that the flow structures in the cavity of the unsteady results are less stable than that of the steady results. The comparison of the upstream and downstream results shows that the downstream sealing flow generally is the mirror image of the upstream sealing flow, while the downstream rim seal performs better as the main flow works on the rotor blades. In addition, the proportions of eigenvalues of the first POD mode demonstrates strong unsteady characters of the flow in the rim seal. The frequency spectra of the POD time coefficient indicate that the most prominent frequency of the flow field in the rim seal is caused by the rotor blade.展开更多
文摘微型反向重复转座元件(MITEs)是一类短的非自主DNA转座子,其分布的位置会对宿主产生影响。文章使用生物信息学的方法对无颌类、软骨鱼纲、肉鳍鱼纲和辐鳍鱼纲鱼类基因组进行了MITEs预测,最终在33种鱼类基因组中鉴定出2433个M I T E s家族。文章发现鱼类基因组中M I T E s含量存在较大差异(0.11%—21.18%),并且MITEs含量与鱼类基因组大小呈正相关关系。根据末端重复序列(TIRs)和靶位点重复序列(TSDs)的特征将MITEs分为10个超家族,其中TC1-Mariner超家族的含量最高。MITEs在鱼类基因组中的插入事件主要发生在4百万年前至今,大多数物种的MITEs在2百万—0.5百万年前发生了爆发式扩增。鱼类基因组中的MITEs多数插入到基因内部或附近,这些转座子可能在基因的表达调控方面存在重要作用。
基金National Natural Science Foundation of China,Grant No.51776011。
文摘For purpose of a more comprehensive understanding of the flow in the disk cavities, the sealing flow in both the upstream and downstream disk-cavity system of a 1.5 stage turbine is investigated by means of CFD methods.The result indicates that the flow structures in the cavity of the unsteady results are less stable than that of the steady results. The comparison of the upstream and downstream results shows that the downstream sealing flow generally is the mirror image of the upstream sealing flow, while the downstream rim seal performs better as the main flow works on the rotor blades. In addition, the proportions of eigenvalues of the first POD mode demonstrates strong unsteady characters of the flow in the rim seal. The frequency spectra of the POD time coefficient indicate that the most prominent frequency of the flow field in the rim seal is caused by the rotor blade.