AIM:To search for new inhibitors with excellent activity and stability to (H ++K +)ATPase.METHOD:Beginning with 2-amino-6-chloro-3-nitropyridine,the title compounds were obtained by substitutioin,cyclization and oxida...AIM:To search for new inhibitors with excellent activity and stability to (H ++K +)ATPase.METHOD:Beginning with 2-amino-6-chloro-3-nitropyridine,the title compounds were obtained by substitutioin,cyclization and oxidation.RESULT:Five new compounds were synthesized and the structure of the title compounds was identified by IR, 1HNMR and ESI-MS.Activity and stability of the five new compounds are on searching.展开更多
文摘AIM:To search for new inhibitors with excellent activity and stability to (H ++K +)ATPase.METHOD:Beginning with 2-amino-6-chloro-3-nitropyridine,the title compounds were obtained by substitutioin,cyclization and oxidation.RESULT:Five new compounds were synthesized and the structure of the title compounds was identified by IR, 1HNMR and ESI-MS.Activity and stability of the five new compounds are on searching.
