Baicalein,the aglycon of baicalin,is one of the main bioactive flavones in Scutellaria baicalensis Georsi.Five metabolites（M1-M5）and the parent drug（MO）were identified in rat serum after oral administration of bai...Baicalein,the aglycon of baicalin,is one of the main bioactive flavones in Scutellaria baicalensis Georsi.Five metabolites（M1-M5）and the parent drug（MO）were identified in rat serum after oral administration of baicalein at a dose of 200 mg/kg using the HPLC-DAD and LC-MS/MS methods.Based on the results,the possible metabolic pathway of baicalein in rat serum was proposed.展开更多
基金National Natural Science Foundation of China (Grant No.30225049).
文摘Baicalein,the aglycon of baicalin,is one of the main bioactive flavones in Scutellaria baicalensis Georsi.Five metabolites（M1-M5）and the parent drug（MO）were identified in rat serum after oral administration of baicalein at a dose of 200 mg/kg using the HPLC-DAD and LC-MS/MS methods.Based on the results,the possible metabolic pathway of baicalein in rat serum was proposed.
