Four pyridazinone gluosodes 4 were synthesized by Koenig′s Knorr reaction of 6 (4 halophenyl) 3( 2H ) pyridazinone silver salt 2 with bromoacetylglucose 3.Treatment of 4 with dry ammonia at 0～-5℃ effected a removal...Four pyridazinone gluosodes 4 were synthesized by Koenig′s Knorr reaction of 6 (4 halophenyl) 3( 2H ) pyridazinone silver salt 2 with bromoacetylglucose 3.Treatment of 4 with dry ammonia at 0～-5℃ effected a removal of the acetyl protecting groups to yield compounds 5.When the substituent on the benaene ring was F or Cl ,O glucoside was synthesized principally.However,when the substituent was Br or I ,N glucoside was mainly obtained.Their structures were confirmed by 1H NMR,IR and elemental analysis.展开更多
The palladium acetate-catalyzed synthesis of benzophenone in the mixture of water and ionic liquid is described. The Pd(OAc)2-H2O-[bmim][PF6]catalytic system is a desired green midium and is superior to the previous m...The palladium acetate-catalyzed synthesis of benzophenone in the mixture of water and ionic liquid is described. The Pd(OAc)2-H2O-[bmim][PF6]catalytic system is a desired green midium and is superior to the previous methods in organic systems in terms of reaction conditions, efficiency, and reaction time. It can be recovered and reused eight times with high efficiency and the use of expensive and environmentally unfavorable phosphine ligand is avoided.展开更多
文摘Four pyridazinone gluosodes 4 were synthesized by Koenig′s Knorr reaction of 6 (4 halophenyl) 3( 2H ) pyridazinone silver salt 2 with bromoacetylglucose 3.Treatment of 4 with dry ammonia at 0～-5℃ effected a removal of the acetyl protecting groups to yield compounds 5.When the substituent on the benaene ring was F or Cl ,O glucoside was synthesized principally.However,when the substituent was Br or I ,N glucoside was mainly obtained.Their structures were confirmed by 1H NMR,IR and elemental analysis.
文摘The palladium acetate-catalyzed synthesis of benzophenone in the mixture of water and ionic liquid is described. The Pd(OAc)2-H2O-[bmim][PF6]catalytic system is a desired green midium and is superior to the previous methods in organic systems in terms of reaction conditions, efficiency, and reaction time. It can be recovered and reused eight times with high efficiency and the use of expensive and environmentally unfavorable phosphine ligand is avoided.
