A new sustainable antibacterial surgical suture coated by chitosan-levofloxacin microcapsule(CLM) was developed and characterized in this work.The CLM with a mean diameter of 1.0-10.0 μm was prepared by emulsion solv...A new sustainable antibacterial surgical suture coated by chitosan-levofloxacin microcapsule(CLM) was developed and characterized in this work.The CLM with a mean diameter of 1.0-10.0 μm was prepared by emulsion solvent evaporation method and applied to the silk surgical suture as the main element of antibacterial coating by dipping-rolling coating method.By the agar diffusion method,high anti-microbial efficacy for up to 4 d was observed against either Staphylococcus aureus(S.aureus) or Escherichia coli(E.coli).And the mechanical properties of the new antibacterial suture including knot mechanical properties,bending stiffness,and suture-to-suture friction properties were characterized fulfilling the requirements of surgical sutures,and were superior to the references.展开更多
文摘A new sustainable antibacterial surgical suture coated by chitosan-levofloxacin microcapsule(CLM) was developed and characterized in this work.The CLM with a mean diameter of 1.0-10.0 μm was prepared by emulsion solvent evaporation method and applied to the silk surgical suture as the main element of antibacterial coating by dipping-rolling coating method.By the agar diffusion method,high anti-microbial efficacy for up to 4 d was observed against either Staphylococcus aureus(S.aureus) or Escherichia coli(E.coli).And the mechanical properties of the new antibacterial suture including knot mechanical properties,bending stiffness,and suture-to-suture friction properties were characterized fulfilling the requirements of surgical sutures,and were superior to the references.
