目的:探讨OCTA检查在视网膜静脉阻塞诊疗中的重要应用价值。方法:采用回顾性病例对照研究,选取2018-01/10于大连市第三人民医院眼科门诊确诊为视网膜静脉阻塞的患者38例38眼,其患病眼为A组,对侧健康眼为B组。所有患者均接受OCTA对黄斑...目的:探讨OCTA检查在视网膜静脉阻塞诊疗中的重要应用价值。方法:采用回顾性病例对照研究,选取2018-01/10于大连市第三人民医院眼科门诊确诊为视网膜静脉阻塞的患者38例38眼,其患病眼为A组,对侧健康眼为B组。所有患者均接受OCTA对黄斑区视网膜行3mm×3mm范围的模式扫描,获得表层视网膜、深层视网膜、外层视网膜及脉络膜毛细血管层4个层面黄斑血流密度图,测量表层视网膜中心凹无血管区面积(FAZ),Image J软件计算4个层面黄斑区血流密度(MVD),OCT模式测量黄斑中心凹的水平厚度与垂直厚度(CFT)。结果: A组和B组浅层视网膜FAZ、水平CFT及垂直CFT测量均有差异( P <0.01)。A组和B组表层视网膜及深层视网MVD均有差异( P <0.01),外层视网膜层MVD、脉络膜毛细血管层MVD结果无差异( P =0.542、0.489)。BCVA(LogMAR)分别与表层视网膜FAZ、水平CFT及垂直CFT呈正相关( r =0.482、0.652、0.621,均 P <0.01),与表层视网膜MVD及深层视网膜MVD呈负相关( r =-0.486 、-0.465,均 P <0.01)。结论:应用OCTA检查对提示视网膜静脉阻塞患者黄斑区视网膜的微循环障碍和视力预后有重要指导意义。展开更多
目的:探讨不同类型人工泪液眼用凝胶对VDT综合征患者泪膜稳定性的影响。方法:选取2018年1-9月于本院眼科门诊就诊,主诉眼部干涩的VDT综合征患者60例(120眼),将其随机分为三组,每组20例(40眼)。A组应用卡波姆眼用凝胶治疗,B组应用维生素...目的:探讨不同类型人工泪液眼用凝胶对VDT综合征患者泪膜稳定性的影响。方法:选取2018年1-9月于本院眼科门诊就诊,主诉眼部干涩的VDT综合征患者60例(120眼),将其随机分为三组,每组20例(40眼)。A组应用卡波姆眼用凝胶治疗,B组应用维生素A棕榈酸酯眼用凝胶治疗,C组应用小牛血去蛋白提取物眼用凝胶治疗。比较三组治疗前、治疗后7 d、1个月、3个月基础泪液分泌(Schirmer I test,SⅠt)、泪膜破裂时间(break up time,BUT)、角膜荧光素染色(fluorescence,FL)评分情况。结果:三组患者治疗前、治疗7 d后SⅠt、BUT及FL评分比较,差异均无统计学意义(P>0.05)。三组患者治疗1个月后SⅠt及FL评分比较,差异均无统计学意义(P>0.05);C组BUT均明显高于A组与B组,三组BUT比较,差异有统计学意义(P<0.05)。三组患者治疗3个月后SⅠt比较,差异无统计学意义(P>0.05);C组BUT均明显高于A组与B组,三组BUT比较,差异有统计学意义(P<0.05);B组FL评分均明显低于A组和C组,三组FL评分比较,差异有统计学意义(P<0.05)。结论:卡波姆眼用凝胶、维生素A棕榈酸酯眼用凝胶及小牛血去蛋白提取物眼用凝胶在VDT综合征患者的泪膜稳定方面均有一定作用,其中维生素A棕榈酸酯眼用凝胶在角膜上皮修复方面效果显著,而小牛血去蛋白提取物眼用凝胶不但可以促进角膜上皮的修复,而且在增强泪膜稳定性方面更具优势。展开更多
目的:探究玻璃体腔注射康柏西普辅助玻璃体切割术(PPV)治疗增殖型糖尿病视网膜病变(PDR)合并玻璃体积血(VH)的疗效及安全性。方法:前瞻性随机对照研究。选取2017-02/2019-09本院眼科收治的PDR合并VH患者作为研究对象,随机分为观察组(39...目的:探究玻璃体腔注射康柏西普辅助玻璃体切割术(PPV)治疗增殖型糖尿病视网膜病变(PDR)合并玻璃体积血(VH)的疗效及安全性。方法:前瞻性随机对照研究。选取2017-02/2019-09本院眼科收治的PDR合并VH患者作为研究对象,随机分为观察组(39例39眼)及对照组(38例38眼)。两组患者均行经睫状体平坦部标准27G PPV治疗,观察组在术前6~7d进行玻璃体腔内注射康柏西普。收集围手术期指标,随访最佳矫正视力(BCVA)、眼压、黄斑中心凹视网膜厚度(CMT),统计手术相关并发症发生情况。结果:观察组手术时间(74.18±15.26 vs 96.17±14.27min)、出血眼数(8%vs 37%)、硅油填充比例(18%vs 53%)、医源性裂孔发生率(15%vs 47%)少于对照组(P<0.05);观察组术后1mo(0.33±0.10 vs 0.60±0.21)、3mo(0.29±0.08 vs 0.59±0.30)、6mo(0.28±0.10 vs 0.66±0.25)时BCVA(LogMAR)显著优于对照组(P<0.05);观察组术后3mo(252.15±56.96 vs 278.41±57.48μm)、6mo(239.65±41.52 vs 268.59±33.71μm)时CMT显著优于对照组(P<0.05);随访期间观察组及对照组玻璃体出血发生率为5%、21%(P<0.05);对照组术后3眼(8%)出现牵拉性视网膜脱离,观察组未发生牵拉性视网膜脱离(P>0.05)。结论:对于PDR合并VH患者,PPV术前辅助使用玻璃体腔注射康柏西普可缩短手术时间,减少术中出血,减轻黄斑水肿,获得更好的视力,有较好的疗效及安全性。展开更多
This study aims to investigate the seasonal variations in copepod community structure and prosome length of dominant species from March 2009 to January 2010 around artificial reefs in Xiaoshi Island,Yellow Sea,Weihai,...This study aims to investigate the seasonal variations in copepod community structure and prosome length of dominant species from March 2009 to January 2010 around artificial reefs in Xiaoshi Island,Yellow Sea,Weihai,China.Samples were collected using two types of plankton net(Model I and Model II) for different-sized copepods.The number of taxon was calculated from the data of both the net types,while the copepod abundance was done using the samples from Model II only.Sixteen species of planktonic copepods,including 5 dominant species,were recorded.Results reveal that Oithona similis was the first dominant species from March to June,and was replaced by Paracalanus parvus in September;both dominated the copepod community in January.Acartia hongi was the second dominant species from March to September.Centropages abdominalis was the third dominant species from March to June,and was replaced by O.similis in September and Corycaeus affinis in January.C.affinis was the fourth dominant species in September.Population density of the dominant copepods was compared with that of other similar regions.We found that the dominant species were mostly small copepods(<1 mm) except for adult Centrapages abdominalis.Seasonal variation in prosome length of O.similis,C.abdominalis,and C.affinis,and their copepodites were studied for the first time in China.For P.parvus and A.hongi,seasonal trends in prosome length variation were similar with those in Jiaozhou Bay,Yellow Sea,Qingdao,China,in a similar temperate domain.The results are helpful for future calculation of copepod biomass and production,and for investigation of the relationship between copepods and fish resources.展开更多
文摘目的:探讨OCTA检查在视网膜静脉阻塞诊疗中的重要应用价值。方法:采用回顾性病例对照研究,选取2018-01/10于大连市第三人民医院眼科门诊确诊为视网膜静脉阻塞的患者38例38眼,其患病眼为A组,对侧健康眼为B组。所有患者均接受OCTA对黄斑区视网膜行3mm×3mm范围的模式扫描,获得表层视网膜、深层视网膜、外层视网膜及脉络膜毛细血管层4个层面黄斑血流密度图,测量表层视网膜中心凹无血管区面积(FAZ),Image J软件计算4个层面黄斑区血流密度(MVD),OCT模式测量黄斑中心凹的水平厚度与垂直厚度(CFT)。结果: A组和B组浅层视网膜FAZ、水平CFT及垂直CFT测量均有差异( P <0.01)。A组和B组表层视网膜及深层视网MVD均有差异( P <0.01),外层视网膜层MVD、脉络膜毛细血管层MVD结果无差异( P =0.542、0.489)。BCVA(LogMAR)分别与表层视网膜FAZ、水平CFT及垂直CFT呈正相关( r =0.482、0.652、0.621,均 P <0.01),与表层视网膜MVD及深层视网膜MVD呈负相关( r =-0.486 、-0.465,均 P <0.01)。结论:应用OCTA检查对提示视网膜静脉阻塞患者黄斑区视网膜的微循环障碍和视力预后有重要指导意义。
文摘目的:探讨不同类型人工泪液眼用凝胶对VDT综合征患者泪膜稳定性的影响。方法:选取2018年1-9月于本院眼科门诊就诊,主诉眼部干涩的VDT综合征患者60例(120眼),将其随机分为三组,每组20例(40眼)。A组应用卡波姆眼用凝胶治疗,B组应用维生素A棕榈酸酯眼用凝胶治疗,C组应用小牛血去蛋白提取物眼用凝胶治疗。比较三组治疗前、治疗后7 d、1个月、3个月基础泪液分泌(Schirmer I test,SⅠt)、泪膜破裂时间(break up time,BUT)、角膜荧光素染色(fluorescence,FL)评分情况。结果:三组患者治疗前、治疗7 d后SⅠt、BUT及FL评分比较,差异均无统计学意义(P>0.05)。三组患者治疗1个月后SⅠt及FL评分比较,差异均无统计学意义(P>0.05);C组BUT均明显高于A组与B组,三组BUT比较,差异有统计学意义(P<0.05)。三组患者治疗3个月后SⅠt比较,差异无统计学意义(P>0.05);C组BUT均明显高于A组与B组,三组BUT比较,差异有统计学意义(P<0.05);B组FL评分均明显低于A组和C组,三组FL评分比较,差异有统计学意义(P<0.05)。结论:卡波姆眼用凝胶、维生素A棕榈酸酯眼用凝胶及小牛血去蛋白提取物眼用凝胶在VDT综合征患者的泪膜稳定方面均有一定作用,其中维生素A棕榈酸酯眼用凝胶在角膜上皮修复方面效果显著,而小牛血去蛋白提取物眼用凝胶不但可以促进角膜上皮的修复,而且在增强泪膜稳定性方面更具优势。
文摘目的:探究玻璃体腔注射康柏西普辅助玻璃体切割术(PPV)治疗增殖型糖尿病视网膜病变(PDR)合并玻璃体积血(VH)的疗效及安全性。方法:前瞻性随机对照研究。选取2017-02/2019-09本院眼科收治的PDR合并VH患者作为研究对象,随机分为观察组(39例39眼)及对照组(38例38眼)。两组患者均行经睫状体平坦部标准27G PPV治疗,观察组在术前6~7d进行玻璃体腔内注射康柏西普。收集围手术期指标,随访最佳矫正视力(BCVA)、眼压、黄斑中心凹视网膜厚度(CMT),统计手术相关并发症发生情况。结果:观察组手术时间(74.18±15.26 vs 96.17±14.27min)、出血眼数(8%vs 37%)、硅油填充比例(18%vs 53%)、医源性裂孔发生率(15%vs 47%)少于对照组(P<0.05);观察组术后1mo(0.33±0.10 vs 0.60±0.21)、3mo(0.29±0.08 vs 0.59±0.30)、6mo(0.28±0.10 vs 0.66±0.25)时BCVA(LogMAR)显著优于对照组(P<0.05);观察组术后3mo(252.15±56.96 vs 278.41±57.48μm)、6mo(239.65±41.52 vs 268.59±33.71μm)时CMT显著优于对照组(P<0.05);随访期间观察组及对照组玻璃体出血发生率为5%、21%(P<0.05);对照组术后3眼(8%)出现牵拉性视网膜脱离,观察组未发生牵拉性视网膜脱离(P>0.05)。结论:对于PDR合并VH患者,PPV术前辅助使用玻璃体腔注射康柏西普可缩短手术时间,减少术中出血,减轻黄斑水肿,获得更好的视力,有较好的疗效及安全性。
基金Supported by the National Natural Science Foundation of China(No.41106133)the Shandong University Independent Innovation Foundation(No.2011ZRYQ005)the Program of Academy of Marine Research in Weihai(No.000041342080)
文摘This study aims to investigate the seasonal variations in copepod community structure and prosome length of dominant species from March 2009 to January 2010 around artificial reefs in Xiaoshi Island,Yellow Sea,Weihai,China.Samples were collected using two types of plankton net(Model I and Model II) for different-sized copepods.The number of taxon was calculated from the data of both the net types,while the copepod abundance was done using the samples from Model II only.Sixteen species of planktonic copepods,including 5 dominant species,were recorded.Results reveal that Oithona similis was the first dominant species from March to June,and was replaced by Paracalanus parvus in September;both dominated the copepod community in January.Acartia hongi was the second dominant species from March to September.Centropages abdominalis was the third dominant species from March to June,and was replaced by O.similis in September and Corycaeus affinis in January.C.affinis was the fourth dominant species in September.Population density of the dominant copepods was compared with that of other similar regions.We found that the dominant species were mostly small copepods(<1 mm) except for adult Centrapages abdominalis.Seasonal variation in prosome length of O.similis,C.abdominalis,and C.affinis,and their copepodites were studied for the first time in China.For P.parvus and A.hongi,seasonal trends in prosome length variation were similar with those in Jiaozhou Bay,Yellow Sea,Qingdao,China,in a similar temperate domain.The results are helpful for future calculation of copepod biomass and production,and for investigation of the relationship between copepods and fish resources.
