结直肠癌(Colorectal cancer, CRC)是世界上第三大恶性肿瘤,也是癌症相关死亡的第二大原因。结直肠癌合并梗阻的概率达20%,常需要紧急处理,以免发生穿孔、出血等严重并发症。在过去,急诊手术是唯一可用的治疗方法,虽然可及时切除肿瘤,...结直肠癌(Colorectal cancer, CRC)是世界上第三大恶性肿瘤,也是癌症相关死亡的第二大原因。结直肠癌合并梗阻的概率达20%,常需要紧急处理,以免发生穿孔、出血等严重并发症。在过去,急诊手术是唯一可用的治疗方法,虽然可及时切除肿瘤,但却带来高死亡率和并发症率。自膨式金属支架(SEMS)自90年代问世以来,已经越来越多地作为一种微创治疗手段用于结直肠癌梗阻的治疗中。本文就SEMS的发展以及在结直肠癌伴肠梗阻中的应用进行综述。Colorectal cancer (CRC) is the third most common malignant tumor in the world and the second leading cause of cancer-related deaths. Colorectal cancer is associated with a 20% probability of obstruction and often requires emergency management to avoid serious complications such as perforation and bleeding. In the past, emergency surgery was the only available treatment, which allowed for timely removal of the tumor but entailed high mortality and complication rates. Since its introduction in the 1990s, the self-expanding metallic stent (SEMS) has been increasingly used as a minimally invasive treatment in the management of colorectal cancer obstruction. This article reviews the development of SEMS and its application in colorectal cancer with bowel obstruction.展开更多
文摘结直肠癌(Colorectal cancer, CRC)是世界上第三大恶性肿瘤,也是癌症相关死亡的第二大原因。结直肠癌合并梗阻的概率达20%,常需要紧急处理,以免发生穿孔、出血等严重并发症。在过去,急诊手术是唯一可用的治疗方法,虽然可及时切除肿瘤,但却带来高死亡率和并发症率。自膨式金属支架(SEMS)自90年代问世以来,已经越来越多地作为一种微创治疗手段用于结直肠癌梗阻的治疗中。本文就SEMS的发展以及在结直肠癌伴肠梗阻中的应用进行综述。Colorectal cancer (CRC) is the third most common malignant tumor in the world and the second leading cause of cancer-related deaths. Colorectal cancer is associated with a 20% probability of obstruction and often requires emergency management to avoid serious complications such as perforation and bleeding. In the past, emergency surgery was the only available treatment, which allowed for timely removal of the tumor but entailed high mortality and complication rates. Since its introduction in the 1990s, the self-expanding metallic stent (SEMS) has been increasingly used as a minimally invasive treatment in the management of colorectal cancer obstruction. This article reviews the development of SEMS and its application in colorectal cancer with bowel obstruction.
