A LC-MS /MS method was developed for the determination of ten sulfonamides residues in milk.The MS was operated in the positive ion mode using multiple reaction monitoring.The protein of the sample was separated by ac...A LC-MS /MS method was developed for the determination of ten sulfonamides residues in milk.The MS was operated in the positive ion mode using multiple reaction monitoring.The protein of the sample was separated by acetonitrile.The extract was concentrated under the stream of nitrogen.The analytes were separated on a reversed-phase column of ZORBAX SB-C18(5 μm,4.6 mm×150 mm i.d.) by using methanol-acetonitrile-0.2% formic acid 10 mmol/L ammonium acetate solution as the mobile phase and gradient elution.The limits of detection were 0.5 and 1.0 μg/L,respectively,and the recoveries were between 91% and 102%.展开更多
This thesis developed a LC-ESI-TRAP-MS method for twelve β-lactam antibiotics residues in milk.The massspectrometer was operated in the positive ion mode using multiple reaction monitoring.The limit of detection is 1...This thesis developed a LC-ESI-TRAP-MS method for twelve β-lactam antibiotics residues in milk.The massspectrometer was operated in the positive ion mode using multiple reaction monitoring.The limit of detection is 1.0 and 2.0 μg/L.Overall recoveries were between 55.2% and 109.5%.展开更多
文摘A LC-MS /MS method was developed for the determination of ten sulfonamides residues in milk.The MS was operated in the positive ion mode using multiple reaction monitoring.The protein of the sample was separated by acetonitrile.The extract was concentrated under the stream of nitrogen.The analytes were separated on a reversed-phase column of ZORBAX SB-C18(5 μm,4.6 mm×150 mm i.d.) by using methanol-acetonitrile-0.2% formic acid 10 mmol/L ammonium acetate solution as the mobile phase and gradient elution.The limits of detection were 0.5 and 1.0 μg/L,respectively,and the recoveries were between 91% and 102%.
文摘This thesis developed a LC-ESI-TRAP-MS method for twelve β-lactam antibiotics residues in milk.The massspectrometer was operated in the positive ion mode using multiple reaction monitoring.The limit of detection is 1.0 and 2.0 μg/L.Overall recoveries were between 55.2% and 109.5%.
