提出了一种工作在低输入功率环境下的具有功率自适应功能的915 MHz整流电路.该整流电路适用于较宽的输入功率环境,利用一个场效应管作为自适应开关,根据输入功率的大小切换整流电路工作模式,使其能够在一个较宽的输入功率范围内高效整流...提出了一种工作在低输入功率环境下的具有功率自适应功能的915 MHz整流电路.该整流电路适用于较宽的输入功率环境,利用一个场效应管作为自适应开关,根据输入功率的大小切换整流电路工作模式,使其能够在一个较宽的输入功率范围内高效整流.该电路输入端使用双枝节匹配网络将二极管输入阻抗匹配至50?,输出端并联一电容作为直通滤波器,使得输出功率平稳.仿真结果表明:在-16~4 d Bm的输入功率范围内,整流效率高于40%,最高转换效率为66.2%.实测最佳工作频率有所偏移,最高转换效率为47.5%.可见该整流电路采用简单的平面印刷电路工艺,易集成,可用于环境电磁能量收集.展开更多
目的探讨患有自身免疫疾病的MRL/lpr小鼠作为临床干眼研究动物模型的科学性及实用性。方法8周龄M RL/lpr及BLAB/C雌性小鼠各15只,分为实验组、对照组。分别于8、12、16、20周对各组小鼠行酚红棉线实验检测泪液分泌情况;取各组小鼠泪腺...目的探讨患有自身免疫疾病的MRL/lpr小鼠作为临床干眼研究动物模型的科学性及实用性。方法8周龄M RL/lpr及BLAB/C雌性小鼠各15只,分为实验组、对照组。分别于8、12、16、20周对各组小鼠行酚红棉线实验检测泪液分泌情况;取各组小鼠泪腺组织行H-E染色分析其淋巴细胞浸润情况;Western印迹法检测泪腺炎症因子TNF-α和IL-1β的蛋白表达情况。结果实验组小鼠于16~20周时泪液分泌量显著少于对照组(P<0.05),淋巴细胞浸润情况明显高于对照组(P<0.05),泪腺炎症因子TNF-α和IL-1β表达明显高于对照组(P<0.05)。结论 M RL/lpr小鼠是一种稳定、简单实用的干眼研究动物模型,可用于研究干眼炎症的发病机制。展开更多
The excited state intramolecular proton transfer of four derivatives(FM, BFM, BFBC, CCM) of 3-hydroxychromone is investigated.The geometries of different substituents are optimized to study the substituent effects on ...The excited state intramolecular proton transfer of four derivatives(FM, BFM, BFBC, CCM) of 3-hydroxychromone is investigated.The geometries of different substituents are optimized to study the substituent effects on proton transfer.The mechanism of hydrogen bond enhancement is qualitatively elucidated by comparing the infrared spectra, the reduced density gradient, and the frontier molecular orbitals.The calculated electronic spectra are consistent with the experimental results.To quantify the proton transfer, the potential energy curves(PECs) of the four derivatives in S0 and S1 states are scanned.It is concluded that the ability of proton transfer follows the order: FM > BFM > BFBC > CCM.展开更多
文摘提出了一种工作在低输入功率环境下的具有功率自适应功能的915 MHz整流电路.该整流电路适用于较宽的输入功率环境,利用一个场效应管作为自适应开关,根据输入功率的大小切换整流电路工作模式,使其能够在一个较宽的输入功率范围内高效整流.该电路输入端使用双枝节匹配网络将二极管输入阻抗匹配至50?,输出端并联一电容作为直通滤波器,使得输出功率平稳.仿真结果表明:在-16~4 d Bm的输入功率范围内,整流效率高于40%,最高转换效率为66.2%.实测最佳工作频率有所偏移,最高转换效率为47.5%.可见该整流电路采用简单的平面印刷电路工艺,易集成,可用于环境电磁能量收集.
文摘目的探讨患有自身免疫疾病的MRL/lpr小鼠作为临床干眼研究动物模型的科学性及实用性。方法8周龄M RL/lpr及BLAB/C雌性小鼠各15只,分为实验组、对照组。分别于8、12、16、20周对各组小鼠行酚红棉线实验检测泪液分泌情况;取各组小鼠泪腺组织行H-E染色分析其淋巴细胞浸润情况;Western印迹法检测泪腺炎症因子TNF-α和IL-1β的蛋白表达情况。结果实验组小鼠于16~20周时泪液分泌量显著少于对照组(P<0.05),淋巴细胞浸润情况明显高于对照组(P<0.05),泪腺炎症因子TNF-α和IL-1β表达明显高于对照组(P<0.05)。结论 M RL/lpr小鼠是一种稳定、简单实用的干眼研究动物模型,可用于研究干眼炎症的发病机制。
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11874241,11847224,and 11804195)the Shandong Province Higher Educational Science and Technology Program,China(Grant No.J15LJ03)+1 种基金the Taishan Scholar Project of Shandong Province,China,China Post-Doctoral Foundation(Grant No.2018M630796)the Natural Science Foundation of Shandong Province,China(Grant No.ZR2018BA034)
文摘The excited state intramolecular proton transfer of four derivatives(FM, BFM, BFBC, CCM) of 3-hydroxychromone is investigated.The geometries of different substituents are optimized to study the substituent effects on proton transfer.The mechanism of hydrogen bond enhancement is qualitatively elucidated by comparing the infrared spectra, the reduced density gradient, and the frontier molecular orbitals.The calculated electronic spectra are consistent with the experimental results.To quantify the proton transfer, the potential energy curves(PECs) of the four derivatives in S0 and S1 states are scanned.It is concluded that the ability of proton transfer follows the order: FM > BFM > BFBC > CCM.