After attaching to the uterus,mammalian blastocysts undergo tremendous morphological changes and cell lineage specification events.Failure to execute these correctly results in abnormal development characterized by fe...After attaching to the uterus,mammalian blastocysts undergo tremendous morphological changes and cell lineage specification events.Failure to execute these correctly results in abnormal development characterized by fetal malformation or failure of pregnancy.Due to differences to primate development,it is difficult to translate the knowledge obtained in the mouse model to humans.展开更多
基金supported by the Department of Science and Technology of Guangdong Province(2021ZT09Y233)the National Natural Science Foundation of China(32100653)the Guangzhou Municipal Science and Technology Bureau(202201010891)。
文摘After attaching to the uterus,mammalian blastocysts undergo tremendous morphological changes and cell lineage specification events.Failure to execute these correctly results in abnormal development characterized by fetal malformation or failure of pregnancy.Due to differences to primate development,it is difficult to translate the knowledge obtained in the mouse model to humans.