Microbial asparaginase has been shown to have antitumor activity for lymphosarcoma, and carcinosarcoma, and is particularly effective in the treatment for acute lumphocytic leukemia. Since the 1960s, asparaginase puri...Microbial asparaginase has been shown to have antitumor activity for lymphosarcoma, and carcinosarcoma, and is particularly effective in the treatment for acute lumphocytic leukemia. Since the 1960s, asparaginase purified from E. coli has been used clinically and found to be a very effective antileukemia agent but with certain side effects. In recent years, asparaginases from other bacteria, such as展开更多
Transposon Tn 233(CH) encoding resistance to streptomycin, sulfonamide and mercuric salt was originally resident on Shigella flexneri plasmid DR233. In order to study its molecular characters, Tn233(CH) was transposed...Transposon Tn 233(CH) encoding resistance to streptomycin, sulfonamide and mercuric salt was originally resident on Shigella flexneri plasmid DR233. In order to study its molecular characters, Tn233(CH) was transposed to plasmid pBR322, and展开更多
文摘Microbial asparaginase has been shown to have antitumor activity for lymphosarcoma, and carcinosarcoma, and is particularly effective in the treatment for acute lumphocytic leukemia. Since the 1960s, asparaginase purified from E. coli has been used clinically and found to be a very effective antileukemia agent but with certain side effects. In recent years, asparaginases from other bacteria, such as
文摘Transposon Tn 233(CH) encoding resistance to streptomycin, sulfonamide and mercuric salt was originally resident on Shigella flexneri plasmid DR233. In order to study its molecular characters, Tn233(CH) was transposed to plasmid pBR322, and
