OBJECTIVE: To investigate the relative effects of degree and distribution of body fat with several cardiovascular disease (CVD) risk factors in elderly Chinese subjects. METHODS: One hundred and thirty-five elderly Ch...OBJECTIVE: To investigate the relative effects of degree and distribution of body fat with several cardiovascular disease (CVD) risk factors in elderly Chinese subjects. METHODS: One hundred and thirty-five elderly Chinese individuals (age range, 60-65 y) without any history of significant renal, hepatic or cardiac disease were recruited. Seated blood pressure, anthropometric and fasting plasma biochemical parameters were measured. Student's t-test was used to compare the differences in biochemical and anthropometric markers between cohorts. RESULTS: Males were heavier (64.6 +/- 8.6, 57.2 +/- 8.2kg, P展开更多
Type 2 diabetes (T2D) is characterised by defects in both fasting and postprandial glucose (PPG) control. Many Asians including Chinese people with T2D have isolated high PPG at diagnosis without concomitant elevation...Type 2 diabetes (T2D) is characterised by defects in both fasting and postprandial glucose (PPG) control. Many Asians including Chinese people with T2D have isolated high PPG at diagnosis without concomitant elevation in fasting plasma glucose (FPG). This might be due to differences in genetic architecture, low insulin secretion, and high carbohydrate diet in East Asians. Excursions in PPG contribute significantly to glycemic variability (GV).展开更多
基金supported by the Hong Kong Research Grants Council(grants CUHK 425/95M and CUHK 4095/00M and CUHK Strategic Researeh Programme 9702).
文摘OBJECTIVE: To investigate the relative effects of degree and distribution of body fat with several cardiovascular disease (CVD) risk factors in elderly Chinese subjects. METHODS: One hundred and thirty-five elderly Chinese individuals (age range, 60-65 y) without any history of significant renal, hepatic or cardiac disease were recruited. Seated blood pressure, anthropometric and fasting plasma biochemical parameters were measured. Student's t-test was used to compare the differences in biochemical and anthropometric markers between cohorts. RESULTS: Males were heavier (64.6 +/- 8.6, 57.2 +/- 8.2kg, P
文摘Type 2 diabetes (T2D) is characterised by defects in both fasting and postprandial glucose (PPG) control. Many Asians including Chinese people with T2D have isolated high PPG at diagnosis without concomitant elevation in fasting plasma glucose (FPG). This might be due to differences in genetic architecture, low insulin secretion, and high carbohydrate diet in East Asians. Excursions in PPG contribute significantly to glycemic variability (GV).