To study the role of frontal neurons in pain and acupuncture analgesia, experiments were carried out on 4 monkeys (Macaca mulatta) during performing two tasks, the Heat Discrimination Response GO/NO-GO Task (Task Ⅰ) ...To study the role of frontal neurons in pain and acupuncture analgesia, experiments were carried out on 4 monkeys (Macaca mulatta) during performing two tasks, the Heat Discrimination Response GO/NO-GO Task (Task Ⅰ) and the Heat Delayed Discrimination GO/NO-GO Task (Task Ⅱ). After a criterion of 90% of correct performances over three successive days had been reached, activity of single neurons was recorded from the frontal cortex. Of 276 Task Ⅰ-related neurons, 211 responded to noxious and/or innocuous heat stimuli. Of 73 Task Ⅱ-related neurons, 59 responded to noxious and/or innocuous heat stimuli. During acupuncture, the nociceptive reaction time for lever release to avoid painful stimuli was increased, the percentage of correct performances was lowered, and the neuronal responses to noxious and/or innocuous stimuli were suppressed. These neurons were mainly located in a circumscribed area medial to the superior ramus of the arcuate sulcus in frontal cortex, including the prefrontal and premotor展开更多
The descending pathways of the bulbar vasoconstrictor centre have been repeatedly described in the literature. Lim et al. demonstrated that the excitatory fibres from the bulbar pressor area descended in the ipsilater...The descending pathways of the bulbar vasoconstrictor centre have been repeatedly described in the literature. Lim et al. demonstrated that the excitatory fibres from the bulbar pressor area descended in the ipsilateral ventrolateral column of the spinal cord without decussation and the inhibitory fibres from the depressor area partially decussated in the bulb. Later, Wang et al. reported that partial crossing of the excitatory fibres seemed to occur in the bulb also. Since most physiological studies of the pathways of vasoconstrictor centre in the past were carried out mainly with the response of blood pres-展开更多
文摘To study the role of frontal neurons in pain and acupuncture analgesia, experiments were carried out on 4 monkeys (Macaca mulatta) during performing two tasks, the Heat Discrimination Response GO/NO-GO Task (Task Ⅰ) and the Heat Delayed Discrimination GO/NO-GO Task (Task Ⅱ). After a criterion of 90% of correct performances over three successive days had been reached, activity of single neurons was recorded from the frontal cortex. Of 276 Task Ⅰ-related neurons, 211 responded to noxious and/or innocuous heat stimuli. Of 73 Task Ⅱ-related neurons, 59 responded to noxious and/or innocuous heat stimuli. During acupuncture, the nociceptive reaction time for lever release to avoid painful stimuli was increased, the percentage of correct performances was lowered, and the neuronal responses to noxious and/or innocuous stimuli were suppressed. These neurons were mainly located in a circumscribed area medial to the superior ramus of the arcuate sulcus in frontal cortex, including the prefrontal and premotor
文摘The descending pathways of the bulbar vasoconstrictor centre have been repeatedly described in the literature. Lim et al. demonstrated that the excitatory fibres from the bulbar pressor area descended in the ipsilateral ventrolateral column of the spinal cord without decussation and the inhibitory fibres from the depressor area partially decussated in the bulb. Later, Wang et al. reported that partial crossing of the excitatory fibres seemed to occur in the bulb also. Since most physiological studies of the pathways of vasoconstrictor centre in the past were carried out mainly with the response of blood pres-
