Myocardial ischemia-reperfusion injury(I/R)is a disease in which acute ischaemic myocardium is not restored or even worsened after reperfusion therapy,resulting in arrhythmias and restricted systolic function of the h...Myocardial ischemia-reperfusion injury(I/R)is a disease in which acute ischaemic myocardium is not restored or even worsened after reperfusion therapy,resulting in arrhythmias and restricted systolic function of the heart.circular RNAs are a class of stable non-coding RNAs with a circular structure.circRNAs are involved in the pathogenesis of I/R and have great potential to become new therapeutic targets.This paper,we will review the relationship between the different pathogenesis of I/R and circRNAs.展开更多
Background The most effective treatment for Acute myocardial infarction(AMI)is timely and effective reperfusion therapy;however,the process of reperfusion therapy can worsen the myocardial damage.This pathological pro...Background The most effective treatment for Acute myocardial infarction(AMI)is timely and effective reperfusion therapy;however,the process of reperfusion therapy can worsen the myocardial damage.This pathological process is known as myocardial ischemia-reperfusion injury(I/R).But,the mechanism of I/R is not fully understood and there is no available effective treatment for I/R.This article will review the mechanisms of occurrence and treatments currently found for I/R.展开更多
文摘Myocardial ischemia-reperfusion injury(I/R)is a disease in which acute ischaemic myocardium is not restored or even worsened after reperfusion therapy,resulting in arrhythmias and restricted systolic function of the heart.circular RNAs are a class of stable non-coding RNAs with a circular structure.circRNAs are involved in the pathogenesis of I/R and have great potential to become new therapeutic targets.This paper,we will review the relationship between the different pathogenesis of I/R and circRNAs.
文摘Background The most effective treatment for Acute myocardial infarction(AMI)is timely and effective reperfusion therapy;however,the process of reperfusion therapy can worsen the myocardial damage.This pathological process is known as myocardial ischemia-reperfusion injury(I/R).But,the mechanism of I/R is not fully understood and there is no available effective treatment for I/R.This article will review the mechanisms of occurrence and treatments currently found for I/R.
