An arbitrary three-phase shifting algorithm is introduced in order to achieve full range spectral optical coherence tomography imaging of biological tissue. Theoretical treatment behind this approach is given and expe...An arbitrary three-phase shifting algorithm is introduced in order to achieve full range spectral optical coherence tomography imaging of biological tissue. Theoretical treatment behind this approach is given and experimentally verified. It is shown that this method is capable of eliminating the undesired auto-correlation and complex conjugate images, leading to the un-obscured full range spectral OCT imaging. An intact porcine eye is used to demonstrate the potential of such a method for biological imaging.展开更多
We demonstrated a method for measurement of central corneal thickness(CCT) with a sub-micrometer sensitivity using a spectral domain optical coherence tomography system without needing a super broad bandwidth light so...We demonstrated a method for measurement of central corneal thickness(CCT) with a sub-micrometer sensitivity using a spectral domain optical coherence tomography system without needing a super broad bandwidth light source. By combining the frequency and phase components of Fourier transform, the method is capable of measurement of a large dynamic range with a high sensitivity. Absolute phases are retrieved by comparing the correlations between the detected and simulated interference fringes. The phase unwrapping ability of the present method was quantitatively tested by measuring the displacement of a piezo linear stage. The human CCTs of six volunteers were measured to verify its clinical application. It provides a potential tool for clinical diagnosis and research applications in ophthalmology.展开更多
We demonstrate a system for measuring the ocular axial length （AL） with high sensitivity and high speed using spectral-domain low-coherence interferometry （SD-LCI）. To address the limit in measuring such a large r...We demonstrate a system for measuring the ocular axial length （AL） with high sensitivity and high speed using spectral-domain low-coherence interferometry （SD-LCI）. To address the limit in measuring such a large range by using SD-LCI, we propose a full-range method to recognize the positive and negative depths. The reference arm length is changed synchronously with the shift of the focal point of the probing beam. The system provides a composite depth range that is sufficient to cover the whole eye. We demonstrate the performance of the presented system by measuring the ALs of five volunteers. This system can provide the A-scan ocular biometric assessment of the corneal thickness and AL in 0.1 s.展开更多
文摘An arbitrary three-phase shifting algorithm is introduced in order to achieve full range spectral optical coherence tomography imaging of biological tissue. Theoretical treatment behind this approach is given and experimentally verified. It is shown that this method is capable of eliminating the undesired auto-correlation and complex conjugate images, leading to the un-obscured full range spectral OCT imaging. An intact porcine eye is used to demonstrate the potential of such a method for biological imaging.
基金supported in part by the National Natural Science Foundation of China(NSFC)(Nos.61275214,31170956,and 61771119)the Natural Science Foundation of Hebei Province,China(Nos.A2015501065 and H2015501133)the Fundamental Research Funds for Central Universities(No.N172304034)
文摘We demonstrated a method for measurement of central corneal thickness(CCT) with a sub-micrometer sensitivity using a spectral domain optical coherence tomography system without needing a super broad bandwidth light source. By combining the frequency and phase components of Fourier transform, the method is capable of measurement of a large dynamic range with a high sensitivity. Absolute phases are retrieved by comparing the correlations between the detected and simulated interference fringes. The phase unwrapping ability of the present method was quantitatively tested by measuring the displacement of a piezo linear stage. The human CCTs of six volunteers were measured to verify its clinical application. It provides a potential tool for clinical diagnosis and research applications in ophthalmology.
基金supported in part by the National Natural Science Foundation of China(NSFC)(Nos.61275214,31170956,and 61771119)the Hebei Provincial Natural Science Foundation of China(Nos.A2015501065 and H2015501133)
文摘We demonstrate a system for measuring the ocular axial length （AL） with high sensitivity and high speed using spectral-domain low-coherence interferometry （SD-LCI）. To address the limit in measuring such a large range by using SD-LCI, we propose a full-range method to recognize the positive and negative depths. The reference arm length is changed synchronously with the shift of the focal point of the probing beam. The system provides a composite depth range that is sufficient to cover the whole eye. We demonstrate the performance of the presented system by measuring the ALs of five volunteers. This system can provide the A-scan ocular biometric assessment of the corneal thickness and AL in 0.1 s.
