目的探讨多层螺旋CT肺动脉成像中对比剂用量以及注射速率的优化选择，从而减少含碘对比剂使用过程中的副作用。方法24例患者按对比剂注射速率不同分成3组（3．0ml／s、3．5ml／s、4．0ml／s），对比剂总量均为50ml，进行胸部同层动脉扫...目的探讨多层螺旋CT肺动脉成像中对比剂用量以及注射速率的优化选择，从而减少含碘对比剂使用过程中的副作用。方法24例患者按对比剂注射速率不同分成3组（3．0ml／s、3．5ml／s、4．0ml／s），对比剂总量均为50ml，进行胸部同层动脉扫描，计算主肺动脉干峰值时间（time to peak）、强化峰值（peak contrast enhancement）以及强化CT值大于200Hu起始时间（Tb200）及持续时间（T200）。结果3组之间强化峰值随注射速率加快而增高且三组之间差异均有显著性。T200在3．0ml组与3．5ml／s组差异无显著性（8-10秒，P〉0．05），3．5ml／s组与4．0ml／s组差异有统计学意义（P〈0．05）。结论在16层螺旋CT肺动脉成像检查中，注射速率3．5ml／s、对比剂总量减少至50ml左右可达到检查要求。展开更多
Summary： The aim of this study was to develop a less invasive trans-septal approach for the endo- scopic management of sphenoid sinus lesions. We performed a septal-assisted surgical procedure for endoscopic sphenoid...Summary： The aim of this study was to develop a less invasive trans-septal approach for the endo- scopic management of sphenoid sinus lesions. We performed a septal-assisted surgical procedure for endoscopic sphenoidectomy in 38 patients with isolated or combined sphenoidal sinus lesions, including fungal balls, mucoceles, purulent cystic sphenoidal sinusitis, etc. The posterior portion of the nasal sep- turn became flexible after removal of the vomer and the sphenoidal rostrum. The superior portion of the common meatus was expanded to accommodate the endoscope after the septum was repositioned con- tra-laterally. The lesions were individually managed through the enlarged ostiums while damage to the mucosa of the front sphenoidal wall was avoided. All the procedures were completed successfully without intraoperative complications, and the bony ostiums were identified easily and enlarged accu- rately. During the follow-up period of 16 weeks to 2 years, no re-atresia or restenosis was observed. The recurrence rate was 0. No postoperative complications were recorded. All the responses from the pa- tients were satisfactory. It was concluded that endoscopic sphenoidectomy assisted by trans-septal ap- proach is a feasible, safe, effective and minimally invasive approach for selected cases with unilateral or bilateral lesions in the sphenoid sinuses.展开更多
文摘目的探讨多层螺旋CT肺动脉成像中对比剂用量以及注射速率的优化选择，从而减少含碘对比剂使用过程中的副作用。方法24例患者按对比剂注射速率不同分成3组（3．0ml／s、3．5ml／s、4．0ml／s），对比剂总量均为50ml，进行胸部同层动脉扫描，计算主肺动脉干峰值时间（time to peak）、强化峰值（peak contrast enhancement）以及强化CT值大于200Hu起始时间（Tb200）及持续时间（T200）。结果3组之间强化峰值随注射速率加快而增高且三组之间差异均有显著性。T200在3．0ml组与3．5ml／s组差异无显著性（8-10秒，P〉0．05），3．5ml／s组与4．0ml／s组差异有统计学意义（P〈0．05）。结论在16层螺旋CT肺动脉成像检查中，注射速率3．5ml／s、对比剂总量减少至50ml左右可达到检查要求。
基金supported by Zhuhai Medical Scientific Research Fund,China(No.2012D0401990021)
文摘Summary： The aim of this study was to develop a less invasive trans-septal approach for the endo- scopic management of sphenoid sinus lesions. We performed a septal-assisted surgical procedure for endoscopic sphenoidectomy in 38 patients with isolated or combined sphenoidal sinus lesions, including fungal balls, mucoceles, purulent cystic sphenoidal sinusitis, etc. The posterior portion of the nasal sep- turn became flexible after removal of the vomer and the sphenoidal rostrum. The superior portion of the common meatus was expanded to accommodate the endoscope after the septum was repositioned con- tra-laterally. The lesions were individually managed through the enlarged ostiums while damage to the mucosa of the front sphenoidal wall was avoided. All the procedures were completed successfully without intraoperative complications, and the bony ostiums were identified easily and enlarged accu- rately. During the follow-up period of 16 weeks to 2 years, no re-atresia or restenosis was observed. The recurrence rate was 0. No postoperative complications were recorded. All the responses from the pa- tients were satisfactory. It was concluded that endoscopic sphenoidectomy assisted by trans-septal ap- proach is a feasible, safe, effective and minimally invasive approach for selected cases with unilateral or bilateral lesions in the sphenoid sinuses.
