宫腔灌注液态浓缩生长因子对预防宫腔操作术后宫腔粘连的临床观察

目的:观察宫腔灌注液态浓缩生长因子对预防宫腔操作术后宫腔粘连的临床疗效。方法:收集2022年8月至2023年9月就诊于垫江县中医院妇科门诊人流患者共108例,选取随机数字法分为空白对照组、对照组、观察组各36例。宫腔操作术后三组患者予以口服复方大红袍止血片、康妇炎胶囊。在此基础上分别予以对照组宫腔注入赛必妥防粘连剂,观察组宫腔注入液态生长因子纤维蛋白(LPCGF)。三组患者均连续治疗2周。比较三组患者宫腔粘连的形成率、粘连程度、腹痛持续时长、阴道出血量及其持续时间、子宫内膜厚度、月经恢复时间及不良反应。结果:观察组在宫腔粘连的发生率和粘连分级上显著低于对照组和空白对照组(P P P > 0.05)。结论:宫腔灌注液态浓缩生长因子对预防宫腔操作术后宫腔粘连的临床疗效更佳,可显著改善临床症状,降低一系列的不良反应。Objective: To observe the clinical efficacy of uterine cavity instillation of liquid concentrated growth factor on the prevention of uterine adhesion after uterine operation. Methods: A total of 108 abortion patients who visited the gynecology outpatient clinic of Dianjiang County Hospital of Traditional Chinese Medicine from August 2022 to September 2023 were collected, and were divided into 36 cases each in the blank control group, the control group, and the observation group by the random number method. After intrauterine operation, the three groups of patients were orally administered compound Dahongpao hemostatic tablets and Kangwenyan capsules. On this basis, the control group was injected with Sebitol anti-adhesion agent into the uterine cavity, and the observation group was injected with liquid growth factor fibrin (LPCGF) into the uterine cavity. 2 weeks of continuous treatment were given to the patients in all three groups. The three groups were treated continuously for 2 weeks, and the rate of formation of uterine adhesions, the degree of adhesion, the duration of abdominal pain, the amount and duration of vaginal bleeding, the thickness of the endometrium, the recovery time of menstruation, and the adverse reactions were compared among the three groups. Results: The incidence rate of uterine adhesions and adhesion grading in the observation group was significantly lower than that in the control group and blank control group (P P P > 0.05). Conclusion: The clinical efficacy of intrauterine infusion of liquid concentrated growth factors in preventing uterine adhesions after uterine operation is better, which can significantly improve clinical symptoms and reduce a series of adverse reactions.

中药熏洗联合康复新液雾化和换药对混合痔术后创面愈合的临床观察

为观察自拟苦参汤熏洗联合康复新液雾化、换药在混合痔术后创面愈合的临床疗效,将2014年2月至2016年2月在我院行外剥内扎术的125例混合痔患者,随机分为2组.治疗组63例应用自拟苦参汤熏洗坐浴后,联合康复新液超声雾化治疗,并给予康复新纱条换药.对照组62例给予高锰酸钾稀释液坐浴和碘伏棉片换药.观察2组患者术后切口疼痛、水肿、创面愈合时间.结果显示,治疗组患者术后切口水肿程度轻,术后疼痛消退快,创面愈合时间明显缩短.2组术后肛缘水肿评分,治疗组术后5 d(0.22±0.39)、7 d(0.04±0.12),对照组5 d(1.52±0.45)、7 d(0.71±0.56);疼痛消退时间治疗组(4.21±1.45)d,对照组(8.12±1.13)d;切口愈合时间治疗组(14.22±1.28)d,对照组(21.34±3.01)d.差异均有统计学意义(P＜0.05).结果表明,运用自拟苦参汤熏洗联合康复新液雾化、换药能有效缓解混合痔术后创面水肿、疼痛、加速创面愈合.

RPH辅以外痔切缝封闭术治疗混合痔的临床研究

为探讨自动痔疮套扎术（RPH）辅以外痔切缝封闭术治疗混合痔的临床疗效,回顾2015年3月至2016年11月我科行手术治疗的165例混合痔患者资料,其中80例行RPH辅以外痔切缝封闭术治疗（治疗组）,85例行外剥内扎术治疗（对照组）.比较2组治愈率、手术时间、术后尿潴留和Ⅱ级以上疼痛发生率、术后出血评分、肛门坠胀消退时间、创面愈合时间.结果显示,治疗组治愈率为97.5％（78/80）,对照组为95.3％（81/85）,差异无统计学意义,P〉0.05.2组患者术后肛门坠胀消退时间比较差异无统计学意义,P〉0.05.治疗组在手术时间、术后尿潴留和Ⅱ级以上疼痛发生率、术后出血评分、创面愈合时间方面明显优于对照组,差异均有统计学意义,P〈0.05.结果表明,与外剥内扎术相比,RPH辅以外痔切缝封闭术治疗混合痔操作简单,疗效确切,并发症少,创面愈合快,更加微创.

气道定植菌对肺癌患者术后肺部感染的影响因素分析

目的探讨气道定植菌对肺癌患者术后肺部感染的影响因素。方法选取2014年2月-2016年10月于医院接受治疗的102例非小细胞肺癌患者为研究对象,手术前经纤维支气管镜及气管内液进行细菌取样,按照样本中是否有气道定植菌将患者分为试验组54例和对照组48例,其中试验组术前患有气道定植菌,对照组术前检测结果为无气道定植菌。术后对其进行血清肺表面活性蛋白D含量(surfactant protein,SP-D)检测,分析肺癌患者术后并发症情况;采集患者术后咳痰行病原菌分析,并归纳肺癌患者术后肺部感染的影响因素。结果试验组肺部感染率为25.93%(14/54)高于对照组6.25%(3/48)(P=0.024)。试验组中出现乳糜胸1例,皮下气肿2例,肺栓塞1例,声音嘶哑1例,试验组并发症患者共19例;对照组中出现乳糜胸1例,声音嘶哑1例,对照组并发症患者共5例低于试验组(P=0.032);试验组患者术前血清SP-D水平(32.01±5.98)ng/ml高于对照组(P=0.042)。感染患者共培养分离病原菌28株,其中革兰阳性菌15株,革兰阴性菌12株,真菌1株;共检出8株定植菌,其中肺炎克雷伯菌2株,铜绿假单胞菌2株,大肠埃希菌1株;金黄色葡萄球菌1株,肺炎链球菌1株;白假丝酵母1株;高龄、术前有气道定植菌是肺癌患者术后肺部感染的影响因素(P<0.05)。结论气道定植菌会增加肺癌患者术后肺部感染概率,而高龄是导致术后肺部感染的关键因素,临床应重点关注此类患者并采取相应的预防措施。