Constructing specific structures from the bottom up with artificial units is an important interdisciplinary topic involving physics,chemistry,materials,and so on.In this work,we theoretically demonstrated the feasibil...Constructing specific structures from the bottom up with artificial units is an important interdisciplinary topic involving physics,chemistry,materials,and so on.In this work,we theoretically demonstrated the feasibility of using superatoms as building blocks to assemble a complex at atomic-level precision.By using a series of actinide-based endohedral metallofullerene(EMF)superatoms that can form one,two,three and four chemical bonds,a planar complex with intra-and inter-molecular interactions was assembled on the Au(111)surface.This complex is composed of two parts,containing ten and eight superatoms,respectively.The electronic structure analysis shows that the electron density inside each part is connected and the closed-shell electronic arrangement system is designed.There is also an obvious van der Waals boundary by physical adsorption between the two parts,and a stable complex is formed.Since this complex is realized by the first-principles calculations of quantum mechanics,our results help not only achieve atomic-level precision construction with artificial superatomic units but also maintain atomic-level functional properties.展开更多
目的探究银屑病对女性妊娠结局及胎儿结局的影响。方法在PubMed、Web of Science、Cochrane Database、中国知网、万方和维普数据库检索从建库至2021年9月公开发表的关于银屑病对女性妊娠结局及胎儿结局影响的文献,根据纳入排除标准筛...目的探究银屑病对女性妊娠结局及胎儿结局的影响。方法在PubMed、Web of Science、Cochrane Database、中国知网、万方和维普数据库检索从建库至2021年9月公开发表的关于银屑病对女性妊娠结局及胎儿结局影响的文献,根据纳入排除标准筛选文献并提取信息,所得数据使用Revman 5.4软件进行统计学分析。结果共纳入16篇队列研究,暴露组和对照组分别纳入27185次银屑病合并妊娠和7860643次健康妊娠。暴露组剖宫产[RR=1.18,95%CI(1.08-1.29),P<0.001]、早产[RR=1.37,95%CI(1.20-1.55),P<0.001]、死产[RR=1.28,95%CI(1.08-1.51),P<0.001]、妊娠期高血压[RR=1.67,95%CI(1.36-2.05),P<0.001]、妊娠期糖尿病[RR=1.56,95%CI(1.31-1.87),P<0.001]、子痫前期/子痫[RR=1.35,95%CI(1.05-1.74),P=0.02]、出生低体重[RR=1.29,95%CI(1.10-1.52),P<0.001]、出生高体重[RR=2.77,95%CI(1.41-5.42),P<0.001]、小于胎龄儿[RR=1.07,95%CI(1.01-1.12),P=0.001]发生率均高于对照组,差异有统计学意义。结论银屑病可能增加女性不良妊娠结局和胎儿不良结局的风险,需在临床工作中进行早期干预。展开更多
Dental caries is the most common bacterial disease afflicting human beings and has long been taken seriously both by the public health authorities and by professional dentists. Since the sixities, as Streptococcus mut...Dental caries is the most common bacterial disease afflicting human beings and has long been taken seriously both by the public health authorities and by professional dentists. Since the sixities, as Streptococcus mutans has been implicated as a causative agent of dental caries, the etiological role of this organism has been the subject of laborious research and considerable progress has been made on the cultivation, metabolism, an-展开更多
基金supported by the National Natural Science Foundation of China(Grant Nos.11974136,11674123,and 11374004)
文摘Constructing specific structures from the bottom up with artificial units is an important interdisciplinary topic involving physics,chemistry,materials,and so on.In this work,we theoretically demonstrated the feasibility of using superatoms as building blocks to assemble a complex at atomic-level precision.By using a series of actinide-based endohedral metallofullerene(EMF)superatoms that can form one,two,three and four chemical bonds,a planar complex with intra-and inter-molecular interactions was assembled on the Au(111)surface.This complex is composed of two parts,containing ten and eight superatoms,respectively.The electronic structure analysis shows that the electron density inside each part is connected and the closed-shell electronic arrangement system is designed.There is also an obvious van der Waals boundary by physical adsorption between the two parts,and a stable complex is formed.Since this complex is realized by the first-principles calculations of quantum mechanics,our results help not only achieve atomic-level precision construction with artificial superatomic units but also maintain atomic-level functional properties.
文摘目的探究银屑病对女性妊娠结局及胎儿结局的影响。方法在PubMed、Web of Science、Cochrane Database、中国知网、万方和维普数据库检索从建库至2021年9月公开发表的关于银屑病对女性妊娠结局及胎儿结局影响的文献,根据纳入排除标准筛选文献并提取信息,所得数据使用Revman 5.4软件进行统计学分析。结果共纳入16篇队列研究,暴露组和对照组分别纳入27185次银屑病合并妊娠和7860643次健康妊娠。暴露组剖宫产[RR=1.18,95%CI(1.08-1.29),P<0.001]、早产[RR=1.37,95%CI(1.20-1.55),P<0.001]、死产[RR=1.28,95%CI(1.08-1.51),P<0.001]、妊娠期高血压[RR=1.67,95%CI(1.36-2.05),P<0.001]、妊娠期糖尿病[RR=1.56,95%CI(1.31-1.87),P<0.001]、子痫前期/子痫[RR=1.35,95%CI(1.05-1.74),P=0.02]、出生低体重[RR=1.29,95%CI(1.10-1.52),P<0.001]、出生高体重[RR=2.77,95%CI(1.41-5.42),P<0.001]、小于胎龄儿[RR=1.07,95%CI(1.01-1.12),P=0.001]发生率均高于对照组,差异有统计学意义。结论银屑病可能增加女性不良妊娠结局和胎儿不良结局的风险,需在临床工作中进行早期干预。
文摘Dental caries is the most common bacterial disease afflicting human beings and has long been taken seriously both by the public health authorities and by professional dentists. Since the sixities, as Streptococcus mutans has been implicated as a causative agent of dental caries, the etiological role of this organism has been the subject of laborious research and considerable progress has been made on the cultivation, metabolism, an-
