INTRODUCTION Leptospirosis is a zoonotic infection of worldwide distribution caused by Leptospira interrogans,a pathogenic spirochete.The most important reservoirs are rodents,predominantly rats.Urinary shedding of or...INTRODUCTION Leptospirosis is a zoonotic infection of worldwide distribution caused by Leptospira interrogans,a pathogenic spirochete.The most important reservoirs are rodents,predominantly rats.Urinary shedding of organisms from infected animals is the most significant source of Leptospira spp.The majority of patients presented with a mild,febrile illness similar with common cold,but a subgroup of patients develops a severe form with multiorgan involvement characterized by fever,jaundice,hemorrhagic manifestation such as pulmonary hemorrhage,renal failure,or even multiple organ dysfunction[1].展开更多
文摘INTRODUCTION Leptospirosis is a zoonotic infection of worldwide distribution caused by Leptospira interrogans,a pathogenic spirochete.The most important reservoirs are rodents,predominantly rats.Urinary shedding of organisms from infected animals is the most significant source of Leptospira spp.The majority of patients presented with a mild,febrile illness similar with common cold,but a subgroup of patients develops a severe form with multiorgan involvement characterized by fever,jaundice,hemorrhagic manifestation such as pulmonary hemorrhage,renal failure,or even multiple organ dysfunction[1].
