A multi center randomized clinical trial was adopted in the present study. 1705 eligible women with identical demographic and gynecological characteristics were divided into two groups: 871 using phenol atabrine pas...A multi center randomized clinical trial was adopted in the present study. 1705 eligible women with identical demographic and gynecological characteristics were divided into two groups: 871 using phenol atabrine paste (PAP) and 834 using phenol mucilage (PM). The five year follow up rates for the two groups were 97.5% and 98.1%, respectively. The multiple decrement life table analysis showed that there was a significant difference in the gross cumulative failure rates between the two groups. The 60th month gross cumulative failure rates for PAP group and PM group were 4.61% and 11.87%, respectively, thus indicating the efficacy of PAP to be significantly higher than that of PM. 97.7% users had cervical smear examinations, but no suspected cancer cells or cancer cells were found. Meanwhile, there was no known diseases related to the chemical reagent. This follow up study indicates that tubal sterilization by chemical instillation is a simple,safe and efficient female method. It suggested that this method would be introduced to a wider use on the basis of modification in the composition of chemical agents, standardized operational procedure, and improved administrative regulation in the use of this technology.展开更多
Eighty-four hamsters were vasectomized on both sides,Another group of 76 hamsters was used as the control group.The animal experiment demonstrated that the epididymal function was damaged on the basis of the micropunc...Eighty-four hamsters were vasectomized on both sides,Another group of 76 hamsters was used as the control group.The animal experiment demonstrated that the epididymal function was damaged on the basis of the micropuncture and microanalysis of the epididymal plasma.Histologic examination revealed the dilatation of the lumen,infiltration of chronic inflammatory cells in the interstitium and sperm granuloma.Thirty-nine patients with postvasectomy epididymal stasis were treated with microwave radiation and 10 cases with epididymectomy.The B and C ultrasonography and MRI were used for diagnosis.Histologic examination suggested that chronic obstruction of vasectomy mode(both-side electric coagulation or keeping proximal open)may lead to formation of the new dynamic equilibrium, therefore benefiting the spermatogenesis of testis.Others with acute obstruction of the vas(bilateral ligation) may cause epididymal stasis.展开更多
文摘A multi center randomized clinical trial was adopted in the present study. 1705 eligible women with identical demographic and gynecological characteristics were divided into two groups: 871 using phenol atabrine paste (PAP) and 834 using phenol mucilage (PM). The five year follow up rates for the two groups were 97.5% and 98.1%, respectively. The multiple decrement life table analysis showed that there was a significant difference in the gross cumulative failure rates between the two groups. The 60th month gross cumulative failure rates for PAP group and PM group were 4.61% and 11.87%, respectively, thus indicating the efficacy of PAP to be significantly higher than that of PM. 97.7% users had cervical smear examinations, but no suspected cancer cells or cancer cells were found. Meanwhile, there was no known diseases related to the chemical reagent. This follow up study indicates that tubal sterilization by chemical instillation is a simple,safe and efficient female method. It suggested that this method would be introduced to a wider use on the basis of modification in the composition of chemical agents, standardized operational procedure, and improved administrative regulation in the use of this technology.
文摘Eighty-four hamsters were vasectomized on both sides,Another group of 76 hamsters was used as the control group.The animal experiment demonstrated that the epididymal function was damaged on the basis of the micropuncture and microanalysis of the epididymal plasma.Histologic examination revealed the dilatation of the lumen,infiltration of chronic inflammatory cells in the interstitium and sperm granuloma.Thirty-nine patients with postvasectomy epididymal stasis were treated with microwave radiation and 10 cases with epididymectomy.The B and C ultrasonography and MRI were used for diagnosis.Histologic examination suggested that chronic obstruction of vasectomy mode(both-side electric coagulation or keeping proximal open)may lead to formation of the new dynamic equilibrium, therefore benefiting the spermatogenesis of testis.Others with acute obstruction of the vas(bilateral ligation) may cause epididymal stasis.
