Xylose crystal was obtained from cottonseed hull by the ethanol solventing-out crystallization process.The crystal was analyzed and determined by infrared spectrometer (IR),melting point tester,environmental scanning ...Xylose crystal was obtained from cottonseed hull by the ethanol solventing-out crystallization process.The crystal was analyzed and determined by infrared spectrometer (IR),melting point tester,environmental scanning electron microscope (ESEM),high performance liquid chromatography (HPLC),and particle analyzer.The results showed that this xylose crystal is similar to that came from corncob in the IR spectroscopy and melting point,but their shape is different,the former likes long prism and the later is square.Under the optimized operation conditions,the purity of the crystal could be up to 99.64%(mass),and the yield 77.6%.The particle size at mediam is 151 μm with the variation 47%.These data indicate that ethanol solventing-out crystallization can be an industrial potential method for production of xylose.展开更多
目的评价中国人群以呋喃唑酮为基础的方案在幽门螺杆菌(Helicobacter pylori,H.pylori)初次治疗中的疗效、安全性及溃疡愈合率.方法计算机检索Pub Med(1990-01/2016-05)、E M B A S E(1990-01/2016-05)、万方数据库(1990-01/2016-05)、...目的评价中国人群以呋喃唑酮为基础的方案在幽门螺杆菌(Helicobacter pylori,H.pylori)初次治疗中的疗效、安全性及溃疡愈合率.方法计算机检索Pub Med(1990-01/2016-05)、E M B A S E(1990-01/2016-05)、万方数据库(1990-01/2016-05)、维普中文科技期刊数据库(1990-01/2016-05),收集中国人群以呋喃酮唑为基础的方案初次治疗H.pylori的随机对照试验(randomized controlled trials,RCT)研究,评价纳入研究质量,用Rev Man5.2.4软件进行统计分析.结果共纳入10个RCT,共包含患者1904例,其中呋喃唑酮组958,对照组946例.呋喃唑酮组与对照组H.pylori根除率的ITT分析分别为84.66%与81.92%,P P分析分别为85.55%与83.07%,其RR=1.04,95%CI:1.00-1.08,RR=1.03,95%CI:0.99-1.07,P值分别为0.08、0.10;呋喃唑酮与对照组不良反应发生率分别为12.73%与12.68%,其RR=1.00,95%CI:0.79-1.25,P=0.97;呋喃唑酮组与对照组溃疡愈合率分别为91.92%、92.78%,其RR=0.99,95%CI:0.96-1.02,P=0.59.结论中国人群以呋喃唑酮为基础的方案在H.p ylori初次治疗疗效与对照组相似,溃疡愈合率、药物不良反应发生率与对照组相近,可作为H.pylori一线治疗方案,但还需高质量的RCT来进一步验证.展开更多
文摘Xylose crystal was obtained from cottonseed hull by the ethanol solventing-out crystallization process.The crystal was analyzed and determined by infrared spectrometer (IR),melting point tester,environmental scanning electron microscope (ESEM),high performance liquid chromatography (HPLC),and particle analyzer.The results showed that this xylose crystal is similar to that came from corncob in the IR spectroscopy and melting point,but their shape is different,the former likes long prism and the later is square.Under the optimized operation conditions,the purity of the crystal could be up to 99.64%(mass),and the yield 77.6%.The particle size at mediam is 151 μm with the variation 47%.These data indicate that ethanol solventing-out crystallization can be an industrial potential method for production of xylose.
文摘目的评价中国人群以呋喃唑酮为基础的方案在幽门螺杆菌(Helicobacter pylori,H.pylori)初次治疗中的疗效、安全性及溃疡愈合率.方法计算机检索Pub Med(1990-01/2016-05)、E M B A S E(1990-01/2016-05)、万方数据库(1990-01/2016-05)、维普中文科技期刊数据库(1990-01/2016-05),收集中国人群以呋喃酮唑为基础的方案初次治疗H.pylori的随机对照试验(randomized controlled trials,RCT)研究,评价纳入研究质量,用Rev Man5.2.4软件进行统计分析.结果共纳入10个RCT,共包含患者1904例,其中呋喃唑酮组958,对照组946例.呋喃唑酮组与对照组H.pylori根除率的ITT分析分别为84.66%与81.92%,P P分析分别为85.55%与83.07%,其RR=1.04,95%CI:1.00-1.08,RR=1.03,95%CI:0.99-1.07,P值分别为0.08、0.10;呋喃唑酮与对照组不良反应发生率分别为12.73%与12.68%,其RR=1.00,95%CI:0.79-1.25,P=0.97;呋喃唑酮组与对照组溃疡愈合率分别为91.92%、92.78%,其RR=0.99,95%CI:0.96-1.02,P=0.59.结论中国人群以呋喃唑酮为基础的方案在H.p ylori初次治疗疗效与对照组相似,溃疡愈合率、药物不良反应发生率与对照组相近,可作为H.pylori一线治疗方案,但还需高质量的RCT来进一步验证.
