Detection and Quantification of Anti-Inflammatory Cytokine in Sera and Urine of Sudanese Patients Infected with Schistosoma haematobium

Cytokines have been in focus of scientific in for more than decade now. Analyzing their expression has enabled a better understanding of pathogenesis of various diseases. Moreover, they are now for beyond their stage when they were of interest for pathophysiological research. In the present study, we used an assay to anti-inflammatory cytokines. One hundred and thirty sera and urine from egg positive individuals and 42 samples of healthy individuals in Eldeum locality—an endemic area of S. haematobum and 28 healthy individuals from non-endemic area were tested. Concentration of IL5 and IL10 is reverse. IL5 is low in serum but high in urine before treatment and high in serum and low in urine after treatment. IL10 is high in serum, low in urine before treatment and low in serum, high in urine after treatment.

高极化^3He MRI对100例连续研究对象的生理检测观察和安全性评估

目的评价高极化氦3（^3He）MR成像的安全性。方法本研究经伦理审查委员会批准并取得受试者的知情同意。100例连续受试者[男57例，女43例；平均年龄（52±14）岁1在进行高极化^3HeMR成像之前、过程中及之后分别采集生理检测数据。受试者吸入含有300～500mL的^3He和0～2700mL的N2的混合气体10L，在MR检查中屏气长达15S。在每次检查中采用脉冲血氧监测仪连续检测心率、心律和血红蛋白氧饱和度（SpO2）。分别评价^3HeMR成像对于生命体征和SpO2的影响，以及SpO2最低观测值与肺功能、药物剂量、临床分类（正常志愿者、哮喘病人、大剂量吸烟者、因为严重肺气肿而行肺部减容手术的病人以及肺癌病人）的关系。