Estimation of Reproduction Numbers for the Period of the COVID-19 Epidemic Outbreak in the Central African Republic

In this paper, we propose a susceptible-exposed-infection-asymptomatic-hospitalized-recovered (SEIAHR) model with parameters on retrospective social distancing and masking. We estimated the model parameters from information published on the World Health Organization (WHO) website. We found that the actual reproduction number Rt varies over the period from 03 March to 07 June 2020 and moreover, effective control over contacts and the frequency of population movement would reduce the evolution of the epidemic (control c ≥ 50%). And the contact check has an influence on the base reproduction number R0.

The HIV’s Transmission from the Mother to the Child at the Community Hospital Center of Bangui (Central African Republic)

Objective: Assess the impact of B + option on mother-to-child HIV’s transmission at the community university hospital center after 4 years of use. Patients and methods: This was a retrospective and analytical study from January 1st 2015 to December 31st 2018 i.e. 4 years. The population’s study was on HIV-positive mothers and their infants care in the service. Results: A total of 323 files of infants born from HIV-positive mothers were selected and having performed the PCR. 9 of them were HIV positive representing a rate of 2.79% mother-to-child HIV’s transmission. This prevalence was 1.1% for women who started ART before and during pregnancy. The average age of newborns was 29 years. Mothers were literally rating in 24.15% during the period of starting antiretroviral therapy, 63% during pregnancy and 19% before pregnancy. For the delivery’s way 295 delivered vaginally;they represented 91.33%. Cesarean delivery was 8.67%. Exclusive breastfeeding represented 87.31% of the diet. Mothers who started ARV therapy during the labor and after delivery were more likely to transmit HIV to their infants than mothers who started ART before and during pregnancy (p = 0.01). The other risk factors were represented by premature rupture of the membranes (p = 0.0001), hours of labor (p = 0.0001), use of suction cup (p = 0.0005), birth weight less than 2500 g (p = 0.00). Conclusion: Mother-to-child HIV’s transmission still remains a public health problem at the Community University Hospital.