We report the case of a 57-year-old man who presented bilateral subacute and painless optic neuropathy after meningopolyradiculitis revealing a primary human immunodeficiency virus infection. Both antiretroviral and s...We report the case of a 57-year-old man who presented bilateral subacute and painless optic neuropathy after meningopolyradiculitis revealing a primary human immunodeficiency virus infection. Both antiretroviral and steroid treatments were ineffective. Clinical symptoms and evolutive pattern were consistent with a mechanism of microvascular ischaemia of the optic nerve head. Optic neuropathies related to HIV infection are rare compared to those resulting from opportunistic infections. There are several pathophysiological mechanisms involved.展开更多
Introduction. Mucormycosis is a rare and acute fungal infection which is frequ ently lethal. The rhinocerebral form is usually seen in diabetics, but other localizations may occur in severely immun ocompromised subjec...Introduction. Mucormycosis is a rare and acute fungal infection which is frequ ently lethal. The rhinocerebral form is usually seen in diabetics, but other localizations may occur in severely immun ocompromised subjects. Observation. We report the case of a sphenoidal sinusitis associated with a probable cavernous sinus thrombosis and carotid artery thromb osis with middle cerebral artery territory infarction. Diagnosis was made on his tological examination following sphenoidotomy. Early medical and surgical treatm ent led to a good outcome. Conclusion.The diagnosis of rhinocerebral mucormycosi s should be considered in the clinical setting of necrotic sinusitis and acute n eurologic deficit in diabetic patients. Early diagnosis and treatment are crucia l factors leading to a good outcome.展开更多
文摘We report the case of a 57-year-old man who presented bilateral subacute and painless optic neuropathy after meningopolyradiculitis revealing a primary human immunodeficiency virus infection. Both antiretroviral and steroid treatments were ineffective. Clinical symptoms and evolutive pattern were consistent with a mechanism of microvascular ischaemia of the optic nerve head. Optic neuropathies related to HIV infection are rare compared to those resulting from opportunistic infections. There are several pathophysiological mechanisms involved.
文摘Introduction. Mucormycosis is a rare and acute fungal infection which is frequ ently lethal. The rhinocerebral form is usually seen in diabetics, but other localizations may occur in severely immun ocompromised subjects. Observation. We report the case of a sphenoidal sinusitis associated with a probable cavernous sinus thrombosis and carotid artery thromb osis with middle cerebral artery territory infarction. Diagnosis was made on his tological examination following sphenoidotomy. Early medical and surgical treatm ent led to a good outcome. Conclusion.The diagnosis of rhinocerebral mucormycosi s should be considered in the clinical setting of necrotic sinusitis and acute n eurologic deficit in diabetic patients. Early diagnosis and treatment are crucia l factors leading to a good outcome.
