4-(R-Phenylazo)-2-methyl quinoline derivatives form (1:1) complexes with nickel chloride, nickel acetate and copper acetate which were syntheses. The three complexes are non-electrolyte in dimethylsulfoxide (DMF). The...4-(R-Phenylazo)-2-methyl quinoline derivatives form (1:1) complexes with nickel chloride, nickel acetate and copper acetate which were syntheses. The three complexes are non-electrolyte in dimethylsulfoxide (DMF). The results of electronic and magnetic measurements show that these complexes are of octahedral structures. The oxygen and nitrogen donate their lone-pair electrons to metal ion to form chelates with formula [MLRm.nH2O]. The relative stabilities of the complexes have been calculated from TG curve using Coats-Redfern and Ozawa methods.展开更多
Thermal analysis of some antihypertensive drugs, Telmisartan, Cilazapril and Terazosin HCL was achieved. Thermogravimetry, derivative thermogravimetry and differential thermal analysis were used through the work. Ther...Thermal analysis of some antihypertensive drugs, Telmisartan, Cilazapril and Terazosin HCL was achieved. Thermogravimetry, derivative thermogravimetry and differential thermal analysis were used through the work. Thermogravimetric parameters such as activation energy, frequency factor and reaction order were calculated. The results show the stability value decrease in the order Telmisartan > Cilazapril > Terazosin. This method can be used in the quality control of pharmaceutical compounds because it is simple, fast and cheap.展开更多
文摘4-(R-Phenylazo)-2-methyl quinoline derivatives form (1:1) complexes with nickel chloride, nickel acetate and copper acetate which were syntheses. The three complexes are non-electrolyte in dimethylsulfoxide (DMF). The results of electronic and magnetic measurements show that these complexes are of octahedral structures. The oxygen and nitrogen donate their lone-pair electrons to metal ion to form chelates with formula [MLRm.nH2O]. The relative stabilities of the complexes have been calculated from TG curve using Coats-Redfern and Ozawa methods.
文摘Thermal analysis of some antihypertensive drugs, Telmisartan, Cilazapril and Terazosin HCL was achieved. Thermogravimetry, derivative thermogravimetry and differential thermal analysis were used through the work. Thermogravimetric parameters such as activation energy, frequency factor and reaction order were calculated. The results show the stability value decrease in the order Telmisartan > Cilazapril > Terazosin. This method can be used in the quality control of pharmaceutical compounds because it is simple, fast and cheap.
