Introduction: Neonatal asphyxia (NA) is one of the most likely causes of neuro-developmental abnormalities in children. In Mali it is responsible for half of the early deaths and the third of neonatal mortality. Updat...Introduction: Neonatal asphyxia (NA) is one of the most likely causes of neuro-developmental abnormalities in children. In Mali it is responsible for half of the early deaths and the third of neonatal mortality. Updated data would help understand and improve intervention strategies to reduce mortality. Objective: It is the study of epidemiological and clinical characteristics, the immediate outcome and the factors associated with newborn (NB) mortality with NA. Material and Methods: This was a prospective cross-sectional study from June 27th to September 3rd 2016 about the NBs admitted for NA in the Hospital Teaching Gabriel Touré of Bamako. The clinical and biological data including the prognosis were collected from the health records of women, the liaison sheets and the medical file. The analysis was done using the software Epi info version 3.5.1. Results: 76 NBs were included which represented 23.45% of hospitalizations. The majority (89.5%, n = 68) were admitted to less than 24 hours of life for NA grade III according to the Sarnat classification (43.4%, n = 33). The average age of mothers was 24.17 ± 5.5 years. Almost half (41.3%, n = 31) were primigravida. The most common obstetrical event was dystocia (64.5%, n = 49). The prognosis was poor in grade III anoxia in our patients (56%) of deaths. Conclusion: The périnatal anoxia (PA) is a major health issue in Mali because of its frequency and severity. Monitoring of pregnancies, delivery assisted by skillful and qualified personnel, mastery of neonatal resuscitation techniques are good means of prevention.展开更多
We tested the effects of different fire regimes (with different fire date and fuel load) on grass growth, tree debarking and topkill in a Guinea savanna of West Africa. Different fire intensities were simulated on two...We tested the effects of different fire regimes (with different fire date and fuel load) on grass growth, tree debarking and topkill in a Guinea savanna of West Africa. Different fire intensities were simulated on two plots of 3.72 ha each, delimited in two shrubby savanna of the Lamto reserve (C?te d’Ivoire). Two fire regimes were applied, the mid-season fire (January) and the late fire (April). Two fuel levels (single: C1 and double: C2) have been used. For each fire regime, fire intensity was determined. It increases with the fuel quantity (1259 ± 356 kW·m–1 and 3380 ± 1472 kW·m–1 respectively for C1 and C2). The regrowth speed of grasses is also dependent on the fuel quantity (grasses). It increases with it and is higher after the mid-season fire than the late fire. The average intensity of the mid-season fire (2966 ± 2233 kW·m–1) is not significantly different from that of the late fire (1673 ± 1124 kW·m–1). Damages or debarking caused by fire on adult trees were recorded and are linked to fire intensity. Those damages appear to initiate the external cavity observed on trees, known to be detrimental to tree trunk mechanical resistance. They generally affect adult trees of Crossopteryx febrifuga species which is also the most commonly hollowed species. Mid-season fire remains the recommanded fire regime because it insures a faster regrowth of grasses which leads to the maintenance of equilibrium between grasses and trees.展开更多
Background :Non-Hodgkin lymphomas are the first childhood cancer in sub-Saharan Africa. Objective: The purpose of this study was to assess non-Hodgkin lymphomas cases in our setting. Methodology: A retrospective and d...Background :Non-Hodgkin lymphomas are the first childhood cancer in sub-Saharan Africa. Objective: The purpose of this study was to assess non-Hodgkin lymphomas cases in our setting. Methodology: A retrospective and descriptive study carried out in the pediatric oncology unit of the Gabriel Touré Teaching Hospital Bamako over 10 years from 1st January 2005 to 31th December 2015. Results: We exploited 274 (21.6%) cases of Non-Hodgkin Lymphoma out of 1295 cancer cases registered, the age group 6 - 10 years was the most represented (46.4%);the male sex was predominant with a sex-ratio of 1.8;digestive signs were the most common signs of discovery (44.2%) followed by maxillary swelling (42.7%);the majority of patients (52.9%) consulted between 1 and 3 months after the onset of signs;the malnutrition rate was 39.8%, of which 24.1% were severe cases and 15.7% were moderate rate. Abdominal localization was the most common (43.1%) followed by maxillofacial localization (33.9%). Almost all were Burkitt type cytology (92.7%), the majority (73.4%) were in Murphy stage III. Almost all (96%) had received chemotherapy and the modified LMB 01 protocol was widely used (62.4%). The majority of patients (85%) were chemosensitive at day 7 or after the third cyclophosphamide injection but at the end of induction only 31% were in complete remission. Gastrointestinal toxicity was the most common (37.13%) followed by hematologic toxicity 35.09 %;9.12 % of patients were lost of follow-up and 22.26% died. Tumor progression was the most common cause of death (60.66%) followed by infection (21.31%). Conclusion: In light of these findings, the late diagnosis and the poor management of NHL, as well as the limited ability to primarily treat metabolic complications, explain the high case-fatality rate, hence the important role of early diagnosis and treatment multidisciplinary.展开更多
文摘Introduction: Neonatal asphyxia (NA) is one of the most likely causes of neuro-developmental abnormalities in children. In Mali it is responsible for half of the early deaths and the third of neonatal mortality. Updated data would help understand and improve intervention strategies to reduce mortality. Objective: It is the study of epidemiological and clinical characteristics, the immediate outcome and the factors associated with newborn (NB) mortality with NA. Material and Methods: This was a prospective cross-sectional study from June 27th to September 3rd 2016 about the NBs admitted for NA in the Hospital Teaching Gabriel Touré of Bamako. The clinical and biological data including the prognosis were collected from the health records of women, the liaison sheets and the medical file. The analysis was done using the software Epi info version 3.5.1. Results: 76 NBs were included which represented 23.45% of hospitalizations. The majority (89.5%, n = 68) were admitted to less than 24 hours of life for NA grade III according to the Sarnat classification (43.4%, n = 33). The average age of mothers was 24.17 ± 5.5 years. Almost half (41.3%, n = 31) were primigravida. The most common obstetrical event was dystocia (64.5%, n = 49). The prognosis was poor in grade III anoxia in our patients (56%) of deaths. Conclusion: The périnatal anoxia (PA) is a major health issue in Mali because of its frequency and severity. Monitoring of pregnancies, delivery assisted by skillful and qualified personnel, mastery of neonatal resuscitation techniques are good means of prevention.
基金conducted as part of the RIPIECSA-project in Cote d’Ivoire.
文摘We tested the effects of different fire regimes (with different fire date and fuel load) on grass growth, tree debarking and topkill in a Guinea savanna of West Africa. Different fire intensities were simulated on two plots of 3.72 ha each, delimited in two shrubby savanna of the Lamto reserve (C?te d’Ivoire). Two fire regimes were applied, the mid-season fire (January) and the late fire (April). Two fuel levels (single: C1 and double: C2) have been used. For each fire regime, fire intensity was determined. It increases with the fuel quantity (1259 ± 356 kW·m–1 and 3380 ± 1472 kW·m–1 respectively for C1 and C2). The regrowth speed of grasses is also dependent on the fuel quantity (grasses). It increases with it and is higher after the mid-season fire than the late fire. The average intensity of the mid-season fire (2966 ± 2233 kW·m–1) is not significantly different from that of the late fire (1673 ± 1124 kW·m–1). Damages or debarking caused by fire on adult trees were recorded and are linked to fire intensity. Those damages appear to initiate the external cavity observed on trees, known to be detrimental to tree trunk mechanical resistance. They generally affect adult trees of Crossopteryx febrifuga species which is also the most commonly hollowed species. Mid-season fire remains the recommanded fire regime because it insures a faster regrowth of grasses which leads to the maintenance of equilibrium between grasses and trees.
文摘Background :Non-Hodgkin lymphomas are the first childhood cancer in sub-Saharan Africa. Objective: The purpose of this study was to assess non-Hodgkin lymphomas cases in our setting. Methodology: A retrospective and descriptive study carried out in the pediatric oncology unit of the Gabriel Touré Teaching Hospital Bamako over 10 years from 1st January 2005 to 31th December 2015. Results: We exploited 274 (21.6%) cases of Non-Hodgkin Lymphoma out of 1295 cancer cases registered, the age group 6 - 10 years was the most represented (46.4%);the male sex was predominant with a sex-ratio of 1.8;digestive signs were the most common signs of discovery (44.2%) followed by maxillary swelling (42.7%);the majority of patients (52.9%) consulted between 1 and 3 months after the onset of signs;the malnutrition rate was 39.8%, of which 24.1% were severe cases and 15.7% were moderate rate. Abdominal localization was the most common (43.1%) followed by maxillofacial localization (33.9%). Almost all were Burkitt type cytology (92.7%), the majority (73.4%) were in Murphy stage III. Almost all (96%) had received chemotherapy and the modified LMB 01 protocol was widely used (62.4%). The majority of patients (85%) were chemosensitive at day 7 or after the third cyclophosphamide injection but at the end of induction only 31% were in complete remission. Gastrointestinal toxicity was the most common (37.13%) followed by hematologic toxicity 35.09 %;9.12 % of patients were lost of follow-up and 22.26% died. Tumor progression was the most common cause of death (60.66%) followed by infection (21.31%). Conclusion: In light of these findings, the late diagnosis and the poor management of NHL, as well as the limited ability to primarily treat metabolic complications, explain the high case-fatality rate, hence the important role of early diagnosis and treatment multidisciplinary.
