Bimatoprost is a novel ocular hypotensive agent and a synthetic prostamide analog. Pharmacological evaluation, involving functional and radioligand binding studies on recombinant and natural receptors, showed that bim...Bimatoprost is a novel ocular hypotensive agent and a synthetic prostamide analog. Pharmacological evaluation, involving functional and radioligand binding studies on recombinant and natural receptors, showed that bimatoprost acts through novel, prostamide sensitive receptors. The drug lacks meaningful interaction with known human receptors, including ocular drug tar-展开更多
文摘Bimatoprost is a novel ocular hypotensive agent and a synthetic prostamide analog. Pharmacological evaluation, involving functional and radioligand binding studies on recombinant and natural receptors, showed that bimatoprost acts through novel, prostamide sensitive receptors. The drug lacks meaningful interaction with known human receptors, including ocular drug tar-
