Staphylococcal bullous impetigo in a neonate

An otherwise healthy, full-term neonate presented at day 15 of life to the pediatric emergency with generalized papulo-pustular rash for 2 d. This was finally diagnosed as bullous impetigo caused by Staphylococcus aureus(S. aureus). The skin lesions decreased significantly after starting antibiotic therapy and drainage of blister fluid. There was no recurrence of the lesions on followup. This case of generalized pustular eruption due to S. aureus in a neonate is reported, as it poses a diagnostic dilemma and can have serious consequences if left untreated.

Management Dilemma in Case of Abdominal Pregnancy: A Case Report

Introduction: Abdominal pregnancy is a rare form of ectopic pregnancy demanding high index of suspicion for diagnosis. We present a case of secondary abdominal pregnancy which was missed at a peripheral centre and referred to us with laparostomy wound after attempts were made to terminate it without proper diagnosis which resulted in excessive bleeding. Case Presentation: A 30-year-old primigravida was referred to us from a private clinic with a laparostomy wound. She had gone to the private clinic for termination of her 5-month-old pregnancy. Medical method was attempted initially failing which surgical evacuation was planned at second visit which resulted in excessive bleeding. The patient was opened up, fetus was removed from assumed uterine cavity?and attempted to remove the placenta caused torrential bleeding. The abdominal cavity was?packed and she was referred to a higher centre. Here she was taken up for re-exploration;ectopic sac was separated from neighboring structures, right cornu was found ruptured and was repaired. The patient also had wound dehiscence on post op day 7 for which secondary abdominal closure was done. Conclusion: Secondary abdominal pregnancy poses as a challenge to clinicians working in remote areas with limited diagnostic facilities. The condition may be life threatening if not handled meticulously.

Colorimetric Sensor for Detection of Tabun Mimic Diethyl Cyanophosphonate

Herein,a colorimetric chemosensor(probe 7)was designed and synthesized for sensing diethyl cyanophosphonate(DCNP),a Tabun nerve agent simulant.The sensitive,selective,fast response and photostable probe 7 in dimethylsulfoxide(DMSO)responded to DCNP at low concentrations with visual naked eye color change from pink to pale yellow and displayed unresponsive behaviour against various interferences except for copper ions,which can be differentiated by adding ethylene diamine where the yellow color persisted in the case of DCNP but turned to pink in the case of copper ions.Additionally,the yellow aqueous solution of probe 7 at pH 10 and 12 turned colorless against the response of DCNP.The limit of detection(LOD)of probe 7 was found to be 50 nmol/L in an aqueous basic solution at pH 10 for the detection of DCNP.The formation of the cyclized product was elucidated by 1H and 31P NMR nuclear magnetic resonance(1H NMR,31P NMR),Fourier transform infrared spectroscopy(FTIR),and high-resolution mass spectrometry(HRMS)analysis.The filter paper and silica plate loaded with probe 7 were fabricated for real-time and on-site detection of DCNP.