Available online A mild and efficient photocatalytic-induced radical method has been developed for[4+1]cycloaddition reaction of 1,4-disubstituted 1,2,3-triazoles with N-tosylhydrazides and primary amines.The reaction...Available online A mild and efficient photocatalytic-induced radical method has been developed for[4+1]cycloaddition reaction of 1,4-disubstituted 1,2,3-triazoles with N-tosylhydrazides and primary amines.The reaction is catalyzed by 20 mol%of I2 under metal,azide and oxidant-free conditions.The method is based upon the photocatalytic generation of allyl-type radicals,followed by the iodine-catalyzed production of azoalkenes,which react rapidly with various anilines.展开更多
基金The authors acknowledge the financial support from the National Natural Science Foundation of China(Nos.22061040 and 21562039)the Xinjiang Provincial Natural Science Foundation of China(Nos.2022E01069 and 2020D01C024).
文摘Available online A mild and efficient photocatalytic-induced radical method has been developed for[4+1]cycloaddition reaction of 1,4-disubstituted 1,2,3-triazoles with N-tosylhydrazides and primary amines.The reaction is catalyzed by 20 mol%of I2 under metal,azide and oxidant-free conditions.The method is based upon the photocatalytic generation of allyl-type radicals,followed by the iodine-catalyzed production of azoalkenes,which react rapidly with various anilines.
